Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | DHODH | Q02127 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.39 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | CCR4 | P51679 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5850472 | 0.76 | ALDH1A1 (0.50) | ALDH1A1TDP1HDAC6MEN1KMT2A | |
| SCHEMBL9851135 | 0.71 | TDP1 (0.59) | ALDH1A1TDP1GAAPLA2G7PKM | |
| SCHEMBL788751 | 0.67 | ALDH1A1 (0.54) | ALDH1A1TDP1MEN1KMT2AMAPT | |
| SCHEMBL899333 | 0.65 | ALDH1A1 (0.59) | ALDH1A1TDP1MEN1KMT2AMAPT | |
| SCHEMBL31069449 | 0.65 | ALDH1A1 (0.59) | ALDH1A1TDP1MEN1KMT2ANPSR1 | |
| SCHEMBL11159476 | 0.65 | ALDH1A1 (0.59) | ALDH1A1TDP1HDAC6MEN1KMT2A | |
| SCHEMBL18550722 | 0.65 | ALDH1A1 (0.59) | ALDH1A1TDP1MEN1KMT2AMAPT | |
| SCHEMBL899473 | 0.65 | ALDH1A1 (0.57) | ALDH1A1TDP1MEN1KMT2AMAPT | |
| SCHEMBL3529264 | 0.64 | ALDH1A1 (0.47) | ALDH1A1TDP1MEN1KMT2AMAPT | |
| SCHEMBL28924950 | 0.64 | CYP1A2 (0.64) | ALDH1A1TDP1MAPTGAAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5008280-A | Treatment of glutamate-induced convulsions, schizophrenia | RHONE-POULENC SANTE (FR) | 1991-04-16 | — | — | US | disclosed |