Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | RGS12 | O14924 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11135325 | 0.86 | OPRM1 (0.41) | ALDH1A1LMNAMEN1MAPTHPGD | |
| SCHEMBL9278793 | 0.83 | PTPN1 (0.36) | ALDH1A1MEN1MAPTHPGDKMT2A | |
| SCHEMBL628764 | 0.78 | ALOX5 (0.41) | RECQLOPRM1OPRD1OPRK1ALOX5 | |
| SCHEMBL5573303 | 0.76 | PTPN1 (0.40) | ALDH1A1LMNAMEN1MAPTHPGD | |
| SCHEMBL1550059 | 0.74 | ALDH1A1 (0.50) | ALDH1A1LMNAMEN1MAPTHPGD | |
| Bromide SCHEMBL9175713 | 0.72 | ALDH1A1 (0.48) | ALDH1A1LMNAMEN1MAPTHPGD | |
| SCHEMBL9279818 | 0.72 | GABRA1 (0.43) | ALDH1A1LMNAMEN1MAPTHPGD | |
| SCHEMBL9757638 | 0.71 | OPRM1 (0.34) | ALDH1A1LMNAMAPTOPRM1OPRD1 | |
| SCHEMBL1018958 | 0.71 | ESR1 (0.45) | ALDH1A1LMNAMEN1MAPTHPGD | |
| SCHEMBL10970326 | 0.69 | ESR1 (0.41) | ALDH1A1MAPTTDP1OPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0246112-B1 | PREPARATION OF DIAMINO- AND DIALKYLAMINOBENZENEDIOLS | THE DOW CHEMICAL COMPANY (US) | 1991-06-12 | — | — | EP | claimed |