Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPC5 | Q9UL62 | 2/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | PDE4A | P27815 | 1/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.46 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.46 |
| ▸ | BRD4 | O60885 | 2/20 | 0.45 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.45 |
| ▸ | HTR3B | O95264 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | HTR3A | P46098 | 1/20 | 0.45 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.45 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.45 |
| ▸ | RAD52 | P43351 | 1/20 | 0.45 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11473098 | 0.79 | SSTR5 (0.52) | SIGMAR1TP53MAPTPDE4APDE4B | |
| Hydrochloric Acid SCHEMBL9760488 | 0.79 | POLB (0.48) | TP53MAPTPDE4APDE4BPDE4C | |
| SCHEMBL9761998 | 0.77 | KDM4E (0.53) | TP53PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL9761903 | 0.74 | PDE4A (0.50) | TP53PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL9762192 | 0.73 | KDM4E (0.49) | PDE4APDE4BPDE4CPDE4DBRD4 | |
| SCHEMBL9761718 | 0.73 | SLC6A9 (0.49) | TRPC5NPSR1 | |
| Hydrochloric Acid SCHEMBL9761957 | 0.72 | KDM4E (0.48) | PDE4APDE4BPDE4CPDE4DBRD4 | |
| SCHEMBL2244026 | 0.72 | HTR3E (0.61) | MAPTHTR3EHTR3BHTR1AHTR2C | |
| SCHEMBL1152528 | 0.72 | SSTR5 (0.56) | SIGMAR1TP53MAPTHTR1AHTR2C | |
| SCHEMBL11480430 | 0.71 | SSTR5 (0.50) | TP53PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5023256-A | Antihistamines | DOMPE FARMACEUTICI S.P.A. (IT) | 1991-06-11 | — | — | US | disclosed |