Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.50 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.50 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.50 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.50 |
| ▸ | BRD4 | O60885 | 2/20 | 0.49 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.46 |
| ▸ | HRH1 | P35367 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fumaric Acid SCHEMBL9761875 | 0.84 | TP53 (0.50) | LMNAKCNH2CYP2D6CHRM1HRH1 | |
| Fumaric Acid SCHEMBL9761877 | 0.84 | TP53 (0.50) | LMNAKCNH2CYP2D6CHRM1HRH1 | |
| SCHEMBL11473098 | 0.81 | SSTR5 (0.52) | PDE4APDE4BPDE4CPDE4DBRD4 | |
| SCHEMBL9761998 | 0.79 | KDM4E (0.53) | PDE4APDE4BPDE4CPDE4DBRD4 | |
| SCHEMBL12354296 | 0.78 | HTR3E (0.47) | PDE4APDE4BPDE4CPDE4DAVPR1A | |
| SCHEMBL15244750 | 0.76 | TAAR1 (0.48) | PDE4APDE4BPDE4CPDE4DBRD4 | |
| SCHEMBL9762192 | 0.75 | KDM4E (0.49) | PDE4APDE4BPDE4CPDE4DBRD4 | |
| SCHEMBL9760633 | 0.74 | LMNA (0.61) | PDE4APDE4BPDE4CPDE4DBRD4 | |
| Hydrochloric Acid SCHEMBL9761957 | 0.74 | KDM4E (0.48) | PDE4APDE4BPDE4CPDE4DBRD4 | |
| SCHEMBL9760758 | 0.74 | TRPC5 (0.52) | PDE4APDE4BPDE4CPDE4DBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5071855-A | Antihistamines, antiallergens | DOMPE FARMACEUTICI SPA (IT) | 1991-12-10 | — | — | US | disclosed |
| EP-0397614-A2 | Pharmacologically active piperdinylimidazopyridines | DOMPE' FARMACEUTICI S.p.A. (IT) | 1990-11-14 | — | — | EP | disclosed |