Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ADH1B | P00325 | 1/20 | 0.32 |
| ▸ | ADH1C | P00326 | 1/20 | 0.32 |
| ▸ | ADH1A | P07327 | 1/20 | 0.32 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.32 |
| ▸ | PNP | P00491 | 4/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
| ▸ | PDE4A | P27815 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18823486 | 0.78 | — | — | |
| SCHEMBL18712322 | 0.78 | — | — | |
| SCHEMBL18823383 | 0.78 | — | — | |
| SCHEMBL28300488 | 0.77 | AKR1B1 (0.38) | AKR1B1LMNAL3MBTL1TDP1ADH1B | |
| SCHEMBL10433346 | 0.75 | — | — | |
| SCHEMBL6826702 | 0.75 | — | — | |
| SCHEMBL19191850 | 0.75 | AKR1B1 (0.32) | AKR1B1 | |
| SCHEMBL30443114 | 0.75 | AKR1B1 (0.37) | AKR1B1PAX8 | |
| SCHEMBL1813293 | 0.70 | — | — | |
| SCHEMBL6827518 | 0.70 | ADH1B (0.39) | ADH1BADH1CADH1APAX8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5073362-A | DICARBOXYLIC ACID-BIS(3,5-DICARBAMOYL-2,4,6-TRIIODOANILIDES) AND X-RAY CONTRAST MEDIA CONTAINING THEM | SCHERING AKTIENGESELLSCHAFT (DE) | 1991-12-17 | — | — | US | claimed |
| US-8475768-B2 | Paramagnetic chelates thereof and their use as contrast agents in magnetic resonance imaging (MRI) | GE HEALTHCARE AS (NO) | 2013-07-02 | — | — | US | disclosed |
| US-8475768-B2 | Paramagnetic chelates thereof and their use as contrast agents in magnetic resonance imaging (MRI) | GE HEALTHCARE AS (NO) | 2013-07-02 | — | — | US | disclosed |
| US-20110200536-A1 | CHELATORS, PARAMAGNETIC CHELATES THEREOF AND THEIR USE AS CONTRAST AGENTS IN MAGNETIC RESONANCE IMAGING (MRI) | GE HEALTHCARE AS (NO) | 2011-08-18 | — | — | US | disclosed |
| US-20110110865-A1 | CHELATROS, PARAMAGNETIC CHELATES THEREOF AND THEIR USE AS CONTRAST AGENTS IN MAGNETIC RESONANCE IMAGING (MRI) | GE HEALTHCARE AS (NO) | 2011-05-12 | — | — | US | disclosed |
| US-20110110865-A1 | CHELATROS, PARAMAGNETIC CHELATES THEREOF AND THEIR USE AS CONTRAST AGENTS IN MAGNETIC RESONANCE IMAGING (MRI) | GE HEALTHCARE AS (NO) | 2011-05-12 | — | — | US | disclosed |
| WO-2009021948-A1 | CHELATORS, PARAMAGNETIC CHELATES THEREOF AND THEIR USE AS CONTRAST AGENTS IN MAGNETIC RESONANCE IMAGING (MRI) | GE HEALTHCARE AS (NO) | 2009-02-19 | — | — | WO | disclosed |
| WO-2009021947-A1 | CHELATORS, PARAMAGNETIC CHELATES THEREOF AND THEIR USE AS CONTRAST AGENTS IN MAGNETIC RESONANCE IMAGING (MRI) | GE HEALTHCARE AS (NO) | 2009-02-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110110865-A1 | CHELATROS, PARAMAGNETIC CHELATES THEREOF AND THEIR USE AS CONTRAST AGENTS IN MAGNETIC RESONANCE IMAGING (MRI) | TSPO, SHROOM3, GLRX3 | AKR1B1 3515/4885LMNA 4327/4885L3MBTL1 2031/4885 |
| US-20110200536-A1 | CHELATORS, PARAMAGNETIC CHELATES THEREOF AND THEIR USE AS CONTRAST AGENTS IN MAGNETIC RESONANCE IMAGING (MRI) | TSPO, PML, AIP | AKR1B1 2846/4885LMNA 4069/4885L3MBTL1 2385/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.