Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | GALR3 | O60755 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | GPR35 | Q9HC97 | 6/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | TTR | P02766 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13617326 | 0.87 | GPR35 (0.59) | KMT2AMEN1HTTSMN1; SMN2GALR3 | |
| SCHEMBL13616905 | 0.82 | CA1 (0.49) | KMT2AMEN1HTTSMN1; SMN2GALR3 | |
| SCHEMBL3077511 | 0.81 | ALDH1A1 (0.62) | KMT2AMEN1HTTSMN1; SMN2GALR3 | |
| SCHEMBL9642841 | 0.80 | ALDH1A1 (0.44) | KMT2AMEN1HTTSMN1; SMN2GALR3 | |
| SCHEMBL9761462 | 0.80 | CYP19A1 (0.52) | KMT2AMEN1HTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL11223647 | 0.76 | VCAM1 (0.59) | KMT2AGPR35HPGDMAPTCYP1A2 | |
| SCHEMBL10709158 | 0.76 | CASP6 (0.55) | KMT2AMEN1ALDH1A1MAPTTSHR | |
| SCHEMBL18286925 | 0.76 | TDP1 (0.58) | KMT2AMEN1HTTSMN1; SMN2L3MBTL1 | |
| SCHEMBL9761868 | 0.75 | ALDH1A1 (0.46) | KMT2AMEN1HTTSMN1; SMN2ALDH1A1 | |
| Dinoterb SCHEMBL8535102 | 0.75 | KMT2A (0.79) | KMT2AMEN1HTTSMN1; SMN2GALR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1679521-A | Use of substituting nitrobenzene derivative in products preparation | MEN TEWA (CN) | 2005-10-12 | — | — | CN | claimed |
| CN-1193746-C | Substituted nitrobenzene derivatives as pharmaceutical and other beneficial uses | NEN TEWA (CN) | 2005-03-23 | — | — | CN | claimed |
| CN-1294911-A | Substituted nitrobenzene derivatives as pharmaceutical and other beneficial uses | MEN TEWA (CN) | 2001-05-16 | — | — | CN | claimed |
| WO-1998056337-A1 | MALODOR REDUCING COMPOSITION CONTAINING AMBER AND MUSK MATERIALS | THE PROCTER & GAMBLE COMPANY (US) | 1998-12-17 | — | — | WO | claimed |
| US-20180170846-A1 | RESORCINOL DERIVATIVES | SUTTER WEST BAY HOSPITALS | 2018-06-21 | — | — | US | disclosed |
| US-9809521-B2 | Cannabidinoid derivatives | SUTTER WEST BAY HOSPITALS (US) | 2017-11-07 | — | — | US | disclosed |
| US-20160376211-A1 | CANNABIDINOID DERIVATIVES | SUTTER WEST BAY HOSPITALS | 2016-12-29 | — | — | US | disclosed |
| US-9254272-B2 | Resorcinol derivatives | SUTTER WEST BAY HOSPITALS (US) | 2016-02-09 | — | — | US | disclosed |
| US-20130209483-A1 | CANNABIDINOID DERIVATIVES | SUTTER WEST BAY HOSPITALS (US) | 2013-08-15 | — | — | US | disclosed |
| US-20080227869-A1 | Substituted nitrobenzene derivatives as pharmaceutical and other uses thereof | MEN TEWA | 2008-09-18 | — | — | US | disclosed |
| EP-1232748-B1 | USE OF SUBSTITUTED NITROBENZENE DERIVATIVES FOR THE TREATMENT OF DISEASES CAUSED BY BACTERIA, FUNGI AND VIRUSES | MEN TEWA (CN) | 2006-05-03 | — | — | EP | disclosed |
| US-20050228055-A1 | Substituted nitrobenzene derivatives as pharmaceutical and other uses athereof | MEN TEWA | 2005-10-13 | — | — | US | disclosed |
| CN-1679521-A | Use of substituting nitrobenzene derivative in products preparation | MEN TEWA (CN) | 2005-10-12 | — | — | CN | disclosed |
| CN-1193746-C | Substituted nitrobenzene derivatives as pharmaceutical and other beneficial uses | NEN TEWA (CN) | 2005-03-23 | — | — | CN | disclosed |
| EP-1232748-A1 | SUBSTITUTED NITROBENZENE DERIVATIVES AS MEDICINES AND OTHER USEFUL USES THEREOF | Men, Tewa (CN) | 2002-08-21 | — | — | EP | disclosed |
| CN-1294911-A | Substituted nitrobenzene derivatives as pharmaceutical and other beneficial uses | MEN TEWA (CN) | 2001-05-16 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080227869-A1 | Substituted nitrobenzene derivatives as pharmaceutical and other uses thereof | NOS3, NOS1, PTGS1 | KMT2A 2939/4885MEN1 2911/4885HTT 2875/4885 |
| US-20050228055-A1 | Substituted nitrobenzene derivatives as pharmaceutical and other uses athereof | APOB, NDUFB1, CYP2F1 | KMT2A 2654/4885MEN1 2236/4885HTT 1338/4885 |
| US-20130209483-A1 | CANNABIDINOID DERIVATIVES | CNR2, CNR1, GPR18 | KMT2A 1515/4885MEN1 2009/4885HTT 2202/4885 |
| US-20160376211-A1 | CANNABIDINOID DERIVATIVES | CNR2, CNR1, GPR18 | KMT2A 1515/4885MEN1 2009/4885HTT 2202/4885 |
| US-20180170846-A1 | RESORCINOL DERIVATIVES | CNR1, CNR2, RCOR1 | KMT2A 1760/4885MEN1 2269/4885HTT 1733/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.