Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.42 |
| ▸ | LMNA | P02545 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9762467 | 0.78 | MAPT (0.35) | MAPTALDH1A1NPC1RAB9A | |
| SCHEMBL9762405 | 0.77 | MAPT (0.42) | MAPTLMNAALDH1A1NPC1RAB9A | |
| SCHEMBL28786583 | 0.72 | MAPT (0.46) | MAPTLMNAALDH1A1NPC1RAB9A | |
| SCHEMBL9760872 | 0.70 | SMN1; SMN2 (0.46) | MAPTLMNAALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL9761612 | 0.69 | NPSR1 (0.41) | MAPTLMNAALDH1A1NPC1RAB9A | |
| SCHEMBL9762626 | 0.68 | MAPT (0.35) | MAPTALDH1A1 | |
| SCHEMBL11804530 | 0.66 | S1PR4 (0.44) | MAPTLMNAALDH1A1NPC1RAB9A | |
| SCHEMBL10400448 | 0.66 | ALDH1A1 (0.50) | MAPTLMNAALDH1A1NPC1RAB9A | |
| SCHEMBL10400610 | 0.64 | ALDH1A1 (0.40) | MAPTLMNAALDH1A1NPC1RAB9A | |
| SCHEMBL31569228 | 0.64 | MAPT (0.40) | MAPTLMNAALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026694-A | Antitumor agents | THE BRITISH COLUMBIA CANCER FOUNDATION (CA) | 1991-06-25 | — | — | US | disclosed |