Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9762505 | 0.80 | KMT2A (0.44) | SMN1; SMN2MAPK1MAPTKMT2AMEN1 | |
| SCHEMBL9762166 | 0.72 | MAPT (0.46) | SMN1; SMN2MAPK1L3MBTL1MAPTKMT2A | |
| SCHEMBL9761629 | 0.70 | MAPT (0.42) | SMN1; SMN2MAPK1L3MBTL1MAPTKMT2A | |
| SCHEMBL9762467 | 0.68 | MAPT (0.35) | MAPTALDH1A1GAA | |
| SCHEMBL9762513 | 0.67 | MAPT (0.43) | SMN1; SMN2MAPK1L3MBTL1MAPTKMT2A | |
| SCHEMBL9761650 | 0.65 | L3MBTL1 (0.40) | SMN1; SMN2ATML3MBTL1MAPTKMT2A | |
| SCHEMBL6377084 | 0.64 | LMNA (0.58) | SMN1; SMN2MAPK1L3MBTL1MAPTKMT2A | |
| SCHEMBL9762562 | 0.64 | ALDH1A1 (0.38) | MAPK1L3MBTL1MAPTKMT2AMEN1 | |
| SCHEMBL9761852 | 0.64 | L3MBTL1 (0.41) | SMN1; SMN2ATML3MBTL1MAPTKMT2A | |
| SCHEMBL28158993 | 0.64 | SMN1; SMN2 (0.93) | SMN1; SMN2MAPK1ATML3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026694-A | Antitumor agents | THE BRITISH COLUMBIA CANCER FOUNDATION (CA) | 1991-06-25 | — | — | US | disclosed |