Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAT2A | P31153 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9761629 | 0.78 | MAPT (0.42) | MAPTALDH1A1NPC1RAB9A | |
| SCHEMBL9762626 | 0.75 | MAPT (0.35) | MAPTMAT2AALDH1A1 | |
| SCHEMBL9760872 | 0.68 | SMN1; SMN2 (0.46) | MAPTGAAALDH1A1 | |
| SCHEMBL9762405 | 0.68 | MAPT (0.42) | MAPTALDH1A1NPC1RAB9A | |
| SCHEMBL9761612 | 0.67 | NPSR1 (0.41) | MAPTGAAALDH1A1NPC1RAB9A | |
| SCHEMBL9760901 | 0.66 | MAPT (0.33) | MAPT | |
| SCHEMBL11804530 | 0.64 | S1PR4 (0.44) | MAPTALDH1A1NPC1RAB9A | |
| SCHEMBL10400448 | 0.64 | ALDH1A1 (0.50) | MAPTALDH1A1NPC1RAB9A | |
| SCHEMBL10400610 | 0.62 | ALDH1A1 (0.40) | MAPTGAAALDH1A1NPC1RAB9A | |
| SCHEMBL9761257 | 0.59 | CCR6 (0.32) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026694-A | Antitumor agents | THE BRITISH COLUMBIA CANCER FOUNDATION (CA) | 1991-06-25 | — | — | US | disclosed |