Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.38 |
| ▸ | MAPT | P10636 | 7/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9762562 | 0.70 | ALDH1A1 (0.38) | L3MBTL1KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL9762572 | 0.70 | GAA (0.36) | ALDH1A1MAPTHTT | |
| SCHEMBL9761185 | 0.69 | L3MBTL1 (0.40) | L3MBTL1KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL9761168 | 0.68 | GAA (0.35) | ALDH1A1MAPTHPGDHTT | |
| SCHEMBL9762166 | 0.68 | MAPT (0.46) | L3MBTL1KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL14704156 | 0.66 | MAPT (0.49) | L3MBTL1KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL9762357 | 0.66 | L3MBTL1 (0.35) | L3MBTL1KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL9760872 | 0.65 | SMN1; SMN2 (0.46) | L3MBTL1KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL9762544 | 0.63 | GAA (0.31) | — | |
| SCHEMBL9761709 | 0.62 | KMT2A (0.39) | L3MBTL1KMT2AALDH1A1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026694-A | Antitumor agents | THE BRITISH COLUMBIA CANCER FOUNDATION (CA) | 1991-06-25 | — | — | US | disclosed |