Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.45 |
| ▸ | DRD1 | P21728 | 2/20 | 0.45 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
| ▸ | DRD5 | P21918 | 1/20 | 0.45 |
| ▸ | HRH1 | P35367 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7916460 | 0.83 | HTR2A (0.41) | DRD2DRD1DRD4DRD5HRH1 | |
| SCHEMBL777172 | 0.81 | L3MBTL1 (0.40) | TSHRL3MBTL1HPGDSMN1; SMN2KDM4E | |
| SCHEMBL6448097 | 0.76 | BCL2 (0.45) | DRD2DRD1DRD4DRD5CYP1A2 | |
| SCHEMBL11323265 | 0.75 | KDM4E (0.40) | CYP1A2TSHRSMN1; SMN2LMNAKDM4E | |
| SCHEMBL780148 | 0.72 | TSHR (0.39) | CYP1A2CYP3A4TSHRL3MBTL1SMN1; SMN2 | |
| SCHEMBL28674948 | 0.71 | CYP1A2 (0.39) | CYP1A2TSHRL3MBTL1HPGDKDM4E | |
| SCHEMBL621779 | 0.71 | HTR1A (0.58) | DRD2DRD1DRD4DRD5HRH1 | |
| SCHEMBL2816242 | 0.70 | HPGD (0.50) | DRD2DRD1DRD4DRD5HRH1 | |
| SCHEMBL15327763 | 0.70 | KDM4E (0.44) | TSHRHPGDSMN1; SMN2LMNAKDM4E | |
| SCHEMBL10382908 | 0.70 | LTA4H (0.51) | TP53L3MBTL1SMN1; SMN2LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5068425-A | Nervous system disorders, intermediates for drugs and as enantiomorphs | SOCIETE NATIONALE ELF AQUITAINE (FR) | 1991-11-26 | — | — | US | disclosed |
| US-4983768-A | Reacting an organic halide and an oxazaphospholidine in the absence of air, humidity and light | SOCIETE NATIONALE ELF AQUITAINE (FR) | 1991-01-08 | — | — | US | disclosed |