Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | LRRK2 | Q5S007 | 3/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9761404 | 0.73 | KMT2A (0.56) | KMT2AALDH1A1MAPTCYP1A2CYP2C9 | |
| SCHEMBL9761085 | 0.67 | MAPT (0.40) | KMT2AALDH1A1MAPTCYP1A2CYP2C9 | |
| SCHEMBL9762508 | 0.67 | ALDH1A1 (0.43) | KMT2AALDH1A1MAPTCYP1A2CYP2C9 | |
| SCHEMBL27481521 | 0.66 | MAPT (0.45) | KMT2AALDH1A1MAPTCYP1A2CYP2C9 | |
| SCHEMBL27553910 | 0.66 | MAPT (0.48) | KMT2AALDH1A1MAPTCYP1A2CYP2C9 | |
| SCHEMBL9761405 | 0.65 | MAPT (0.46) | ALDH1A1MAPTCYP1A2CYP2C9L3MBTL1 | |
| SCHEMBL9761859 | 0.65 | ALDH1A1 (0.36) | ALDH1A1 | |
| SCHEMBL9761852 | 0.64 | L3MBTL1 (0.41) | KMT2AALDH1A1MAPTCYP1A2CYP2C9 | |
| SCHEMBL17429746 | 0.63 | KMT2A (0.54) | KMT2AALDH1A1MAPTCYP1A2CYP2C9 | |
| SCHEMBL9762557 | 0.63 | MAPT (0.37) | KMT2AALDH1A1MAPTCYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026694-A | Antitumor agents | THE BRITISH COLUMBIA CANCER FOUNDATION (CA) | 1991-06-25 | — | — | US | disclosed |