Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TACR2 | P21452 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9762508 | 0.69 | ALDH1A1 (0.43) | KMT2AMEN1MAPTALDH1A1HTT | |
| SCHEMBL22375160 | 0.69 | GAA (0.46) | L3MBTL1MAPTALDH1A1HTTLMNA | |
| SCHEMBL9761404 | 0.68 | KMT2A (0.56) | L3MBTL1KMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL9761816 | 0.67 | GAA (0.45) | KMT2AMAPTALDH1A1HTTLMNA | |
| SCHEMBL9761839 | 0.64 | KMT2A (0.46) | L3MBTL1ATMKMT2AMAPTALDH1A1 | |
| SCHEMBL9760872 | 0.64 | SMN1; SMN2 (0.46) | L3MBTL1ATMKMT2AMEN1MAPT | |
| SCHEMBL9760917 | 0.64 | GAA (0.45) | L3MBTL1KMT2AMAPTALDH1A1HTT | |
| SCHEMBL9761124 | 0.64 | KMT2A (0.52) | KMT2AMEN1TSHRHSD17B10MAPT | |
| SCHEMBL9762150 | 0.62 | KMT2A (0.48) | L3MBTL1ATMKMT2AMEN1TSHR | |
| SCHEMBL11833197 | 0.62 | ALDH1A1 (0.50) | KMT2AMEN1MAPTALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026694-A | Antitumor agents | THE BRITISH COLUMBIA CANCER FOUNDATION (CA) | 1991-06-25 | — | — | US | disclosed |