Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | PDE1A | P54750 | 1/20 | 0.35 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.35 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.35 |
| ▸ | PARG | Q86W56 | 1/20 | 0.35 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9761743 | 0.77 | BRD4 (0.38) | BRD4PARG | |
| SCHEMBL9761664 | 0.75 | BRD4 (0.47) | BRD4SCN9AALDH1A1 | |
| SCHEMBL9761111 | 0.75 | CYP2C9 (0.38) | BRD4ALDH1A1OPRM1 | |
| SCHEMBL9761584 | 0.72 | BRD4 (0.36) | BRD4PARGSLC6A3 | |
| SCHEMBL9762147 | 0.71 | BRD4 (0.43) | BRD4 | |
| SCHEMBL9760799 | 0.70 | BRD4 (0.37) | BRD4 | |
| SCHEMBL7613547 | 0.69 | ELANE (0.50) | BRD4ALDH1A1 | |
| SCHEMBL2352063 | 0.68 | BRD4 (0.42) | BRD4ALDH1A1 | |
| SCHEMBL9762586 | 0.68 | PARG (0.37) | BRD4PARGDRD2OPRM1 | |
| SCHEMBL10460973 | 0.67 | BRD4 (0.39) | BRD4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5066665-A | Cognition activators; alzheimer*s disease | WARNER-LAMBERT CO. (US) | 1991-11-19 | — | — | US | disclosed |