Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 4/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 4/20 | 0.40 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP12 | P39900 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 3/20 | 0.34 |
| ▸ | BCHE | P06276 | 3/20 | 0.33 |
| ▸ | ACHE | P22303 | 3/20 | 0.33 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9763349 | 0.87 | ADRB2 (0.44) | ADRB2ADRB1ADRB3PDK1KCNH2 | |
| SCHEMBL9763657 | 0.86 | AR (0.38) | ADRB2ADRB1ADRB3MAOBBCHE | |
| SCHEMBL9762553 | 0.83 | CACNA1B (0.34) | ADRB2ADRB1ADRB3MMP2MMP12 | |
| SCHEMBL9762754 | 0.79 | LIMK2 (0.44) | ADRB2ADRB1ADRB3KCNH2 | |
| SCHEMBL9763301 | 0.79 | ADRB2 (0.37) | ADRB2ADRB1ADRB3KCNH2MAOB | |
| SCHEMBL9763623 | 0.78 | AR (0.38) | ADRB2ADRB1ADRB3KCNH2 | |
| Hydrochloric Acid SCHEMBL11671409 | 0.76 | PKM (0.43) | MAOBBCHEACHE | |
| SCHEMBL9763053 | 0.75 | ADRB2 (0.41) | ADRB2ADRB1ADRB3KCNH2MAOB | |
| SCHEMBL9762641 | 0.75 | CCR5 (0.41) | ADRB2ADRB1ADRB3PDK1KCNH2 | |
| Bromide SCHEMBL9762763 | 0.74 | ADRB2 (0.43) | ADRB2ADRB1ADRB3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4990505-A | Treating asthma, bronchitis; adrenergic stimulants | GLAXO GROUP LIMITED (GB) | 1991-02-05 | — | — | US | disclosed |