Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP12 | P39900 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 6/20 | 0.33 |
| ▸ | ACHE | P22303 | 6/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.32 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9763068 | 0.83 | ADRB2 (0.40) | MMP2MMP12BCHEACHEADRB2 | |
| SCHEMBL9763759 | 0.81 | ADRB2 (0.41) | ADRB2ADRB1ADRB3 | |
| Hydrochloric Acid SCHEMBL11671409 | 0.76 | PKM (0.43) | BCHEACHEMAOB | |
| SCHEMBL9763657 | 0.75 | AR (0.38) | BCHEACHEADRB2ADRB1ADRB3 | |
| SCHEMBL10460539 | 0.72 | MAOB (0.38) | BCHEACHEADRB2ADRB1ADRB3 | |
| SCHEMBL10461865 | 0.72 | ADRB2 (0.39) | BCHEACHEADRB2ADRB1ADRB3 | |
| SCHEMBL10477860 | 0.72 | KDM4E (0.41) | BCHEACHEADRB2ADRB1ADRB3 | |
| SCHEMBL10592068 | 0.72 | MAOB (0.40) | BCHEACHEADRB2ADRB1ADRB3 | |
| SCHEMBL9762641 | 0.70 | CCR5 (0.41) | ADRB2ADRB1ADRB3MAOB | |
| SCHEMBL9763673 | 0.70 | ADRB2 (0.40) | ADRB2ADRB1ADRB3MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4990505-A | Treating asthma, bronchitis; adrenergic stimulants | GLAXO GROUP LIMITED (GB) | 1991-02-05 | — | — | US | disclosed |