SCHEMBL9763263

SCHEMBL9763263

O=C(N(CCCCCCOCCCCc1ccc(N2CCOCC2)cc1)Cc1ccccc1)C(F)(F)F

nearest known ligand 0.45

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.45
MAPT P10636 1/20 0.42
MEN1 O00255 1/20 0.41
POLB P06746 1/20 0.41
KMT2A Q03164 1/20 0.41
NAMPT P43490 2/20 0.41
SLC13A5 Q86YT5 1/20 0.40
FAAH O00519 3/20 0.40
CES1 P23141 3/20 0.40
FFAR4 Q5NUL3 1/20 0.40
NAPEPLD Q6IQ20 1/20 0.40
ASAH1 Q13510 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.39
RORC P51449 1/20 0.39
HRH4 Q9H3N8 1/20 0.39
HRH3 Q9Y5N1 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9764529 0.97 L3MBTL1 (0.45) L3MBTL1MAPTMEN1POLBKMT2A
SCHEMBL9763598 0.90 FFAR4 (0.43) MAPTFFAR4SMN1; SMN2HRH4HRH3
SCHEMBL9763406 0.82 FAAH (0.46) FAAHCES1
SCHEMBL9762903 0.79 FAAH (0.42) FAAHCES1
SCHEMBL9762547 0.76 KCNH2 (0.53) MAPTMEN1KMT2AFAAHCES1
SCHEMBL9763073 0.75 FAAH (0.39) FAAHCES1
SCHEMBL9763575 0.75 SPHK1 (0.43) NAMPTFAAHCES1
SCHEMBL9763654 0.74 FAAH (0.39) L3MBTL1FAAHCES1HRH4HRH3
SCHEMBL28287211 0.74 SIGMAR1 (0.60) MAPTMEN1POLBKMT2ASLC13A5
SCHEMBL9762900 0.73 FAAH (0.38) FAAHCES1HRH4HRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4990505-A Treating asthma, bronchitis; adrenergic stimulants GLAXO GROUP LIMITED (GB) 1991-02-05 US disclosed