Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.52 |
| ▸ | HTR6 | P50406 | 2/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | AR | P10275 | 1/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.46 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.46 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9762627 | 0.84 | SIGMAR1 (0.52) | SIGMAR1BCHEARADRB3MAOA | |
| SCHEMBL9763725 | 0.83 | DRD2 (0.51) | SIGMAR1BCHEARADRB1ADRB3 | |
| SCHEMBL10488186 | 0.83 | AR (0.52) | SIGMAR1BCHEMEN1KMT2AAR | |
| SCHEMBL456614 | 0.83 | SIGMAR1 (0.80) | SIGMAR1BCHEMAOACHRM2 | |
| Hydrochloric Acid SCHEMBL9257562 | 0.81 | SIGMAR1 (0.77) | SIGMAR1BCHEMAOACHRM2 | |
| Bromide SCHEMBL7121198 | 0.81 | SIGMAR1 (0.77) | SIGMAR1BCHEMAOACHRM2 | |
| SCHEMBL27496896 | 0.81 | SIGMAR1 (0.77) | SIGMAR1BCHEMAOACHRM2 | |
| Hydrochloric Acid SCHEMBL454214 | 0.81 | SIGMAR1 (0.77) | SIGMAR1BCHEMAOACHRM2 | |
| Hydrochloric Acid SCHEMBL9254084 | 0.81 | SIGMAR1 (0.77) | SIGMAR1BCHEMAOACHRM2 | |
| SCHEMBL10477677 | 0.81 | AR (0.52) | SIGMAR1BCHEMEN1KMT2AAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4990505-A | Treating asthma, bronchitis; adrenergic stimulants | GLAXO GROUP LIMITED (GB) | 1991-02-05 | — | — | US | disclosed |