Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.51 |
| ▸ | DRD3 | P35462 | 2/20 | 0.51 |
| ▸ | DRD4 | P21917 | 1/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.49 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.47 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | AR | P10275 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 2/20 | 0.43 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7907015 | 0.86 | SIGMAR1 (0.64) | DRD2DRD3DRD4SIGMAR1ADRB2 | |
| SCHEMBL9762923 | 0.86 | AR (0.52) | SIGMAR1ADRB2ADRB1ADRB3MAOA | |
| SCHEMBL9764394 | 0.83 | SIGMAR1 (0.69) | SIGMAR1MAOACHRM2BCHE | |
| SCHEMBL10477755 | 0.83 | SIGMAR1 (0.69) | SIGMAR1MAOACHRM2BCHE | |
| SCHEMBL9762627 | 0.83 | SIGMAR1 (0.52) | SIGMAR1ADRB3MAOACHRM2HPGD | |
| SCHEMBL9763280 | 0.83 | SIGMAR1 (0.55) | SIGMAR1ADRB1ADRB3MAOACHRM2 | |
| Hydrochloric Acid SCHEMBL9258435 | 0.82 | SIGMAR1 (0.67) | SIGMAR1MAOACHRM2BCHE | |
| SCHEMBL9763689 | 0.82 | SIGMAR1 (0.52) | SIGMAR1MAOACHRM2BCHE | |
| SCHEMBL9763494 | 0.81 | DRD2 (0.47) | DRD2DRD3DRD4SIGMAR1ADRB2 | |
| SCHEMBL10488186 | 0.81 | AR (0.52) | SIGMAR1ADRB2ADRB1ADRB3HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5006556-A | Dichloroaniline derivatives for the therapy or prophylaxysis of a disease associated with reversible airway obstruction | GLAXO GROUP LIMITED (GB) | 1991-04-09 | — | — | US | disclosed |
| US-4990505-A | Treating asthma, bronchitis; adrenergic stimulants | GLAXO GROUP LIMITED (GB) | 1991-02-05 | — | — | US | disclosed |
| US-4943591-A | TREATMENT OF ASTHMA AND BRONCHITIS | GLAXO GROUP LIMITED (GB) | 1990-07-24 | — | — | US | disclosed |