Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.55 |
| ▸ | HPGD | P15428 | 5/20 | 0.55 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | IDH1 | O75874 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31543779 | 0.86 | L3MBTL1 (0.45) | ALDH1A1HPGDTRPA1CYP3A4ALOX15 | |
| Biphenyl SCHEMBL890280 | 0.85 | ALOX5 (0.55) | ALDH1A1HPGDALOX15L3MBTL1MEN1 | |
| SCHEMBL31543781 | 0.83 | L3MBTL1 (0.50) | ALDH1A1HPGDTRPA1CYP3A4ALOX15 | |
| Diallyldisulfide SCHEMBL28956854 | 0.81 | ALDH1A1 (0.50) | ALDH1A1HPGDTRPA1CYP3A4ALOX15 | |
| Diallyldisulfide SCHEMBL668587 | 0.81 | ALDH1A1 (0.50) | ALDH1A1HPGDTRPA1CYP3A4ALOX15 | |
| SCHEMBL27973299 | 0.79 | ALDH1A1 (0.48) | ALDH1A1HPGDTRPA1CYP3A4ALOX15 | |
| SCHEMBL575899 | 0.76 | HPGD (0.48) | ALDH1A1HPGDTRPA1CYP3A4ALOX15 | |
| SCHEMBL3479361 | 0.76 | RAB9A (0.47) | ALDH1A1HPGDTRPA1CYP3A4ALOX15 | |
| SCHEMBL3479354 | 0.76 | RAB9A (0.47) | ALDH1A1HPGDTRPA1CYP3A4ALOX15 | |
| Diallyldisulfide SCHEMBL28227703 | 0.74 | TRPA1 (0.85) | ALDH1A1HPGDTRPA1CYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4997889-A | Alkylphenol disulfide, aromatic guanidine | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1991-03-05 | — | — | US | disclosed |
| US-4929688-A | Cure system for open steam curing of mineral-loaded chlorobutyl compounds | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1990-05-29 | — | — | US | disclosed |
| US-4873290-A | MIXTURE OF ALKYLPHENOL DISULFIDE AND A GUANIDINE | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1989-10-10 | — | — | US | disclosed |