Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | IGF1R | P08069 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 2/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
| ▸ | BAX | Q07812 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2914383 | 0.91 | TTR (0.50) | TTRPOLBALOX5IGF1RALOX15 | |
| SCHEMBL10984819 | 0.86 | POLB (0.48) | TTRPOLBALOX5LTA4HAKR1B1 | |
| SCHEMBL9764133 | 0.85 | TTR (0.53) | TTRPOLBCAMK2ALTA4HNR1H2 | |
| SCHEMBL2914798 | 0.85 | TNKS2 (0.63) | TTRALOX5AKR1B1 | |
| SCHEMBL2914322 | 0.81 | TNKS2 (0.48) | TTRPOLBALOX5LTA4H | |
| SCHEMBL2910800 | 0.78 | TNKS2 (0.44) | TTRPOLBALOX15LTA4H | |
| SCHEMBL2093898 | 0.78 | LTA4H (0.55) | TTRCAMK2ALTA4HNR1H2BAX | |
| SCHEMBL14621022 | 0.76 | TTR (0.53) | TTRPOLB | |
| SCHEMBL2914006 | 0.75 | F2 (0.56) | TTRPOLBALOX5IGF1RALOX15 | |
| SCHEMBL5079347 | 0.75 | ALDH1A1 (0.48) | TTRPOLBCAMK2ALTA4HNR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0408795-A1 | Improved aromatic polyester film | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1991-01-23 | — | — | EP | disclosed |