Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.65 |
| ▸ | NPC1 | O15118 | 4/20 | 0.65 |
| ▸ | RAB9A | P51151 | 4/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.65 |
| ▸ | TP53 | P04637 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 1/20 | 0.65 |
| ▸ | PKM | P14618 | 1/20 | 0.65 |
| ▸ | HPGD | P15428 | 1/20 | 0.65 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.44 |
| ▸ | LDHA | P00338 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4384430 | 0.82 | SMN1; SMN2 (0.85) | SMN1; SMN2NPC1RAB9AALDH1A1HSD17B10 | |
| SCHEMBL14588328 | 0.80 | SMN1; SMN2 (0.67) | SMN1; SMN2NPC1RAB9AALDH1A1HSD17B10 | |
| SCHEMBL12635465 | 0.80 | SMN1; SMN2 (1.00) | SMN1; SMN2NPC1RAB9AALDH1A1HSD17B10 | |
| SCHEMBL18177599 | 0.79 | SMN1; SMN2 (0.65) | SMN1; SMN2NPC1RAB9AALDH1A1HSD17B10 | |
| SCHEMBL14193958 | 0.76 | SMN1; SMN2 (0.58) | SMN1; SMN2NPC1RAB9AALDH1A1HSD17B10 | |
| SCHEMBL55837 | 0.76 | SMN1; SMN2 (0.54) | SMN1; SMN2NPC1RAB9AALDH1A1HSD17B10 | |
| SCHEMBL33272 | 0.76 | GAA (1.00) | SMN1; SMN2NPC1RAB9AALDH1A1HSD17B10 | |
| SCHEMBL30422583 | 0.76 | GAA (1.00) | SMN1; SMN2NPC1RAB9AALDH1A1HSD17B10 | |
| SCHEMBL3139327 | 0.75 | PI4KA (0.58) | SMN1; SMN2NPC1RAB9AALDH1A1HSD17B10 | |
| SCHEMBL20718749 | 0.75 | KMT2A (0.49) | SMN1; SMN2NPC1RAB9AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115819371-B | Preparation method of benzothiazole-2-formaldehyde and derivatives thereof | 新疆师范大学 | 2024-05-14 | — | — | CN | disclosed |
| CN-115819371-A | Preparation method of benzothiazole-2-formaldehyde and derivatives thereof | 新疆师范大学 | 2023-03-21 | — | — | CN | disclosed |
| US-20220209132-A1 | HETEROCYCLIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME | Changchun Hyperions Technology Co., Ltd. (CN) | 2022-06-30 | — | — | US | disclosed |
| EP-4006025-A1 | HETEROCYCLIC DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE THEREOF | Changchun Hyperions Technology Co., Ltd. (CN) | 2022-06-01 | — | — | EP | disclosed |
| US-11066537-B2 | Composition, film, infrared cut filter, solid image pickup element, infrared sensor, camera module, and novel compound | FUJIFILM CORPORATION (JP) | 2021-07-20 | — | — | US | disclosed |
| US-20210095196-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION (US) | 2021-04-01 | — | — | US | disclosed |
| US-20180105957-A1 | PROCESS FOR MAKING COMPOSITES COMPRISING RIGID-ROD POLYMERS AND GRAPHENE NANOPARTICLES | DANG THUY D (US) | 2018-04-19 | — | — | US | disclosed |
| US-9868977-B2 | Red-shifted luciferins and methods of using same | PROMEGA CORPORATION (US) | 2018-01-16 | — | — | US | disclosed |
| US-9850596-B2 | Composites comprising rigid-rod polymers and graphene nanoparticles and process for making the same | TJC Polymer Inc. (US) | 2017-12-26 | — | — | US | disclosed |
| US-20170314061-A1 | NOVEL LUCIFERASE SEQUENCES UTILIZING INFRARED-EMITTING SUBSTRATES TO PRODUCE ENHANCED LUMINESCENCE | JPMORGAN CHASE BANK, N.A., AS COLLATERAL AGENT | 2017-11-02 | — | — | US | disclosed |
| US-9732373-B2 | Luciferase sequences utilizing infrared-emitting substrates to produce enhanced luminescence | PROMEGA CORPORATION (US) | 2017-08-15 | — | — | US | disclosed |
| US-20170002396-A1 | RED-SHIFTED LUCIFERINS AND METHODS OF USING SAME | JPMORGAN CHASE BANK, N.A., AS COLLATERAL AGENT | 2017-01-05 | — | — | US | disclosed |
| US-9447450-B2 | Red-shifted luciferins and methods of using same | PROMEGA CORPORATION (US) | 2016-09-20 | — | — | US | disclosed |
| US-20160076079-A1 | NOVEL LUCIFERASE SEQUENCES UTILIZING INFRARED-EMITTING SUBSTRATES TO PRODUCE ENHANCED LUMINESCENCE | JPMORGAN CHASE BANK, N.A., AS COLLATERAL AGENT | 2016-03-17 | — | — | US | disclosed |
| US-20150218730-A1 | COMPOSITES COMPRISING RIGID-ROD POLYMERS AND GRAPHENE NANOPARTICLES AND PROCESS FOR MAKING THE SAME | DANG THUY D (US) | 2015-08-06 | — | — | US | disclosed |
| US-20140304842-A1 | RED-SHIFTED LUCIFERINS AND METHODS OF USING SAME | PROMEGA CORPORATION (US) | 2014-10-09 | — | — | US | disclosed |
| US-5053506-A | PHotosensitive viricides | EASTMAN KODAK COMPANY (US) | 1991-10-01 | — | — | US | disclosed |
| US-4937344-A | Novel sulfur-containing merocyanine dyes | EASTMAN KODAK COMPANY (US) | 1990-06-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170002396-A1 | RED-SHIFTED LUCIFERINS AND METHODS OF USING SAME | GUSB, GLB1, MRPL21 | SMN1; SMN2 4398/4885NPC1 844/4885RAB9A 1959/4885 |
| US-20210095196-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | SSB, RO60, OSBP | SMN1; SMN2 4645/4885NPC1 2361/4885RAB9A 428/4885 |
| US-20140304842-A1 | RED-SHIFTED LUCIFERINS AND METHODS OF USING SAME | GUSB, GLB1, MRPL21 | SMN1; SMN2 4398/4885NPC1 844/4885RAB9A 1959/4885 |
| US-20220209132-A1 | HETEROCYCLIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME | EML4, STOM, GJB2 | SMN1; SMN2 2512/4885NPC1 3939/4885RAB9A 1754/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.