Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 4/20 | 0.41 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | NCF1 | P14598 | 1/20 | 0.38 |
| ▸ | ACP1 | P24666 | 1/20 | 0.37 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.37 |
| ▸ | TACR3 | P29371 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9568033 | 0.77 | ACHE (0.37) | ABCB1MEN1KMT2ALMNAMAPT | |
| SCHEMBL8125196 | 0.72 | CYP1A2 (0.40) | ABCB1CLK4MEN1KMT2ALMNA | |
| SCHEMBL8528792 | 0.70 | ALDH1A1 (0.44) | MEN1KMT2ALMNAMAPTRAB9A | |
| SCHEMBL5622659 | 0.69 | ACHE (0.45) | MEN1KMT2AMAOBLMNAMAPT | |
| SCHEMBL8123605 | 0.68 | RAB9A (0.46) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL5670544 | 0.68 | MEN1 (0.40) | CLK4MEN1KMT2ALMNAMAPT | |
| SCHEMBL8529081 | 0.68 | ACHE (0.40) | MEN1KMT2AMAOBMAPTNPC1 | |
| SCHEMBL11195681 | 0.68 | CACNA1B (0.50) | ABCB1ABCG2MEN1KMT2ANCF1 | |
| SCHEMBL8125457 | 0.67 | ACHE (0.39) | MAPTALDH1A1 | |
| SCHEMBL8729761 | 0.67 | GRIN1 (0.43) | MEN1KMT2ALMNAMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5030537-A | Photoconductive unsymmetrical squaraine compositions | XEROX CORPORATION (US) | 1991-07-09 | — | — | US | disclosed |
| US-4922018-A | Photoconductive imaging members with unsymmetrical squaraine compositions | XEROX CORPORATION (US) | 1990-05-01 | — | — | US | disclosed |
| US-4886722-A | Photoconductive imaging members with unsymmetrical squaraine compositions | XEROX CORPORATION (US) | 1989-12-12 | — | — | US | disclosed |