Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT1 | P35610 | 2/20 | 0.55 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.54 |
| ▸ | ACAT1 | P24752 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9765032 | 0.83 | MMP1 (0.48) | SOAT1 | |
| SCHEMBL6743943 | 0.81 | SOAT1 (0.51) | SOAT1SOAT2 | |
| SCHEMBL9765051 | 0.79 | TP53 (0.43) | — | |
| SCHEMBL10587594 | 0.79 | SOAT1 (0.69) | SOAT1SOAT2 | |
| SCHEMBL9263972 | 0.79 | SOAT1 (0.69) | SOAT1SOAT2 | |
| SCHEMBL6746999 | 0.78 | SOAT1 (0.50) | SOAT1 | |
| SCHEMBL9765055 | 0.78 | SOAT1 (0.63) | SOAT1SOAT2 | |
| SCHEMBL9152529 | 0.77 | SOAT1 (0.67) | SOAT1SOAT2 | |
| SCHEMBL9765049 | 0.77 | SOAT2 (0.48) | SOAT1SOAT2ACAT1 | |
| SCHEMBL9679689 | 0.77 | RECQL (0.45) | SOAT1SOAT2ACAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4994465-A | Antihyperlipidemic and antiatherosclerotic trisubstituted urea compounds | WARNER-LAMBERT COMPANY (US) | 1991-02-19 | — | — | US | claimed |
| EP-0384320-A1 | Antihyperlipidemic and anti-atherosclerotic trisubstituted urea compounds | WARNER-LAMBERT COMPANY (US) | 1990-08-29 | — | — | EP | claimed |
| US-4994465-A | Antihyperlipidemic and antiatherosclerotic trisubstituted urea compounds | WARNER-LAMBERT COMPANY (US) | 1991-02-19 | — | — | US | disclosed |
| EP-0384320-A1 | Antihyperlipidemic and anti-atherosclerotic trisubstituted urea compounds | WARNER-LAMBERT COMPANY (US) | 1990-08-29 | — | — | EP | disclosed |