Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.42 |
| ▸ | ACAT1 | P24752 | 1/20 | 0.42 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NMBR | P28336 | 1/20 | 0.38 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9680743 | 0.87 | SOAT1 (0.51) | SOAT2ACAT1SOAT1LMNAMEN1 | |
| SCHEMBL9679685 | 0.85 | SOAT1 (0.48) | SOAT2ACAT1SOAT1LMNAMEN1 | |
| SCHEMBL9679702 | 0.80 | SOAT1 (0.49) | SOAT2ACAT1SOAT1LMNAMEN1 | |
| SCHEMBL9765032 | 0.79 | MMP1 (0.48) | SOAT1ALDH1A1GAAMMP1MMP2 | |
| SCHEMBL9679354 | 0.78 | SOAT1 (0.47) | SOAT2ACAT1SOAT1LMNAMEN1 | |
| SCHEMBL9765041 | 0.77 | SOAT1 (0.55) | SOAT2ACAT1SOAT1 | |
| SCHEMBL9765050 | 0.76 | SOAT1 (0.51) | SOAT2ACAT1SOAT1LMNAALDH1A1 | |
| SCHEMBL9851011 | 0.75 | RECQL (0.48) | RECQLSOAT2SOAT1ALDH1A1GAA | |
| SCHEMBL9765049 | 0.73 | SOAT2 (0.48) | SOAT2ACAT1SOAT1 | |
| SCHEMBL9678897 | 0.71 | SOAT1 (0.57) | SOAT2ACAT1SOAT1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5153226-A | Administering as anticholesterol agents, for atherosclerosis | WARNER-LAMBERT COMPANY (US) | 1992-10-06 | — | — | US | disclosed |
| EP-0415413-A1 | Acat inhibitors | WARNER-LAMBERT COMPANY (US) | 1991-03-06 | — | — | EP | disclosed |