Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G4A | P47712 | 1/20 | 0.45 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | CACNB4 | O00305 | 1/20 | 0.40 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.40 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.40 |
| ▸ | CACNG3 | O60359 | 1/20 | 0.40 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.40 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.40 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.40 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.40 |
| ▸ | CACNG7 | P62955 | 1/20 | 0.40 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.40 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.40 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.40 |
| ▸ | CACNG1 | Q06432 | 1/20 | 0.40 |
| ▸ | CACNB2 | Q08289 | 1/20 | 0.40 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9687878 | 0.87 | HTR1D (0.38) | MEN1KMT2AICMTHTR6IMPDH2 | |
| SCHEMBL9765127 | 0.82 | HTR6 (0.61) | PLA2G4AMTNR1AMTNR1BALDH1A1HDAC1 | |
| SCHEMBL10465857 | 0.78 | CACNB4 (0.46) | PLA2G4ACACNB4CACNA1ACACNA1GCACNG3 | |
| SCHEMBL10465308 | 0.77 | CACNB4 (0.42) | PLA2G4APLA2G2ACACNB4CACNA1ACACNA1G | |
| SCHEMBL10465880 | 0.76 | PLA2G2A (0.47) | PLA2G2ACHRNB2CHRNA7CHRNA4MTNR1A | |
| SCHEMBL10465854 | 0.75 | PLA2G2A (0.46) | PLA2G4APLA2G2AMTNR1AMTNR1BICMT | |
| SCHEMBL274052 | 0.75 | KMT2A (0.63) | CHRNB2CHRNA7CHRNA4MEN1ALDH1A1 | |
| SCHEMBL10494723 | 0.70 | PLA2G4A (0.55) | PLA2G4APLA2G2AMTNR1AMTNR1BICMT | |
| SCHEMBL9765114 | 0.69 | HTR1D (0.65) | LMNAHTR6SNCA | |
| SCHEMBL6707614 | 0.69 | HTR6 (0.60) | CHRNB2CHRNA7CHRNA4MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5037845-A | Analgesics; for treatment or prevention of pain due to vasodilation in the cranium | GLAXO GROUP LIMITED (GB) | 1991-08-06 | — | — | US | disclosed |