Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.66 |
| ▸ | TSHR | P16473 | 1/20 | 0.66 |
| ▸ | ACACB | O00763 | 4/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9513697 | 0.87 | ACACB (0.61) | ALDH1A1TSHRACACBMTNR1AMTNR1B | |
| SCHEMBL22593378 | 0.82 | ALDH1A1 (0.58) | ALDH1A1TSHRACACBMAPTMAPK1 | |
| SCHEMBL9512709 | 0.81 | MTNR1A (0.67) | ALDH1A1ACACBMTNR1AMTNR1BSMN1; SMN2 | |
| SCHEMBL5279314 | 0.80 | ALDH1A1 (1.00) | ALDH1A1TSHRMAPTMAPK1SMN1; SMN2 | |
| SCHEMBL9765290 | 0.79 | PTPN1 (0.55) | ALDH1A1TSHRMAPT | |
| SCHEMBL256524 | 0.79 | ACACB (0.81) | ACACB | |
| SCHEMBL8384245 | 0.77 | MTNR1A (0.60) | ACACBMTNR1AMTNR1BSMN1; SMN2RAB9A | |
| SCHEMBL2091303 | 0.77 | MTNR1A (0.60) | ACACBMTNR1AMTNR1BSMN1; SMN2RAB9A | |
| SCHEMBL8384291 | 0.77 | MTNR1A (0.60) | ACACBMTNR1AMTNR1BSMN1; SMN2RAB9A | |
| SCHEMBL801233 | 0.77 | ALDH1A1 (0.72) | ALDH1A1TSHRMAPTMAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0255728-B1 | PHENOXYACETIC ACID COMPOUNDS, THEIR PREPARATION, PHARMACEUTICAL COMPOSITION AND USE | TANABE SEIYAKU CO., LTD. (JP) | 1991-11-27 | — | — | EP | disclosed |
| US-4866196-A | ANTICOAGULANTS | TANABE SEIYAKU CO., LTD. (JP) | 1989-09-12 | — | — | US | disclosed |
| EP-0255728-A2 | Phenoxyacetic acid compounds, their preparation, pharmaceutical composition and use | TANABE SEIYAKU CO., LTD. (JP) | 1988-02-10 | — | — | EP | disclosed |