Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | GABRP | O00591 | 2/20 | 0.33 |
| ▸ | GABRD | O14764 | 2/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.33 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.33 |
| ▸ | GABRE | P78334 | 2/20 | 0.33 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.33 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fumaric Acid SCHEMBL28356830 | 0.83 | THRB (0.48) | TSHRTHRBPOLBAPEX1HTT | |
| Fumaric Acid SCHEMBL690033 | 0.83 | THRB (0.48) | TSHRTHRBPOLBAPEX1HTT | |
| Maleic Acid SCHEMBL690032 | 0.83 | THRB (0.48) | TSHRTHRBPOLBAPEX1HTT | |
| Maleic Acid SCHEMBL27995521 | 0.80 | THRB (0.43) | TSHRTHRBPOLBAPEX1HTT | |
| Methacrylic Acid SCHEMBL11062934 | 0.79 | GABRP (0.45) | TSHRGABRPGABRDGABRA1GABRB1 | |
| Methacrylic Acid SCHEMBL467445 | 0.78 | THRB (0.53) | TSHRTHRBPOLBAPEX1HTT | |
| Methacrylic Acid SCHEMBL9453862 | 0.78 | THRB (0.53) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL357768 | 0.78 | GABRP (0.50) | TSHRGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL29132467 | 0.77 | HCAR2 (0.53) | TSHRTHRBPOLBAPEX1HTT | |
| Methacrylic Acid SCHEMBL3448070 | 0.77 | TSHR (0.47) | TSHRTHRBPOLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3223377-A | — | — | None | — | — | JP | disclosed |
| JP-H03223377-A | FUNCTIONAL GROUP-CONTAINING SUBSTRATE, PREPARATION OF THE SAME, AND MEDICAL MATERIAL AND EQUIPMENT USING THE SUBSTRATE | TERUMO CORP | 1991-10-02 | — | — | JP | disclosed |