Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 1/20 | 0.43 |
| ▸ | FEN1 | P39748 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.39 |
| ▸ | TUBB | P07437 | 1/20 | 0.39 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.39 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.39 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.39 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.39 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.39 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.39 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.39 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.39 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.39 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.39 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9766040 | 0.83 | GRIN2D (0.47) | NOS2FEN1KDM4EALDH1A1MAPT | |
| SCHEMBL9766046 | 0.78 | L3MBTL1 (0.56) | KDM4ESMN1; SMN2ALDH1A1EGFRKMT2A | |
| SCHEMBL9766070 | 0.75 | PARP1 (0.45) | NOS2FEN1KDM4EALDH1A1KMT2A | |
| SCHEMBL9157807 | 0.73 | KDM4E (0.46) | KDM4ESMN1; SMN2ALDH1A1MAPTHSD17B10 | |
| SCHEMBL506923 | 0.70 | SMN1; SMN2 (0.46) | KDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL9156787 | 0.70 | ALDH1A1 (0.50) | KDM4ESMN1; SMN2ALDH1A1MAPTHSD17B10 | |
| SCHEMBL9159365 | 0.70 | KDM4E (0.49) | KDM4EALDH1A1MAPTHSD17B10KMT2A | |
| SCHEMBL661699 | 0.70 | TAAR1 (0.51) | KDM4ESMN1; SMN2ALDH1A1MAPTKMT2A | |
| SCHEMBL30874634 | 0.70 | TAAR1 (0.51) | KDM4ESMN1; SMN2ALDH1A1MAPTKMT2A | |
| SCHEMBL9156789 | 0.69 | KDM4E (0.49) | KDM4ESMN1; SMN2ALDH1A1MAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4983607-A | ANTISEROTONINERGIC ACTIVITY | SYNTHELABO (FR) | 1991-01-08 | — | — | US | disclosed |