Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | GLA | P06280 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.43 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.43 |
| ▸ | NOS3 | P29474 | 1/20 | 0.41 |
| ▸ | NOS1 | P29475 | 1/20 | 0.41 |
| ▸ | NOS2 | P35228 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | FEN1 | P39748 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9159365 | 0.85 | KDM4E (0.49) | KDM4EALDH1A1GLAHPGDGAA | |
| SCHEMBL9157138 | 0.84 | EGFR (0.44) | KDM4EALDH1A1GLAHPGDGAA | |
| SCHEMBL1776571 | 0.83 | TSHR (0.52) | KDM4EALDH1A1HPGDSMYD3TNKS2 | |
| SCHEMBL9766046 | 0.82 | L3MBTL1 (0.56) | KDM4EALDH1A1HPGDGAATNKS2 | |
| SCHEMBL28836424 | 0.81 | GPR84 (0.58) | ALDH1A1KMT2AMEN1 | |
| SCHEMBL16510780 | 0.78 | LMNA (0.43) | KDM4EALDH1A1HPGDGAASMYD3 | |
| SCHEMBL9156787 | 0.77 | ALDH1A1 (0.50) | KDM4EALDH1A1GLAHPGDGAA | |
| SCHEMBL8369457 | 0.76 | KDM4E (0.59) | KDM4EALDH1A1HPGDGAAKMT2A | |
| SCHEMBL1774421 | 0.76 | FEN1 (0.45) | KDM4EALDH1A1HPGDSMYD3TNKS2 | |
| SCHEMBL4118331 | 0.75 | TNKS2 (0.46) | PARP1KDM4EALDH1A1HPGDSMYD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4983607-A | ANTISEROTONINERGIC ACTIVITY | SYNTHELABO (FR) | 1991-01-08 | — | — | US | disclosed |