Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adipic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 4/20 | 0.58 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.58 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.58 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.53 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.48 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.48 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | PPARG | P37231 | 4/20 | 0.46 |
| ▸ | PPARD | Q03181 | 4/20 | 0.46 |
| ▸ | PPARA | Q07869 | 4/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adipic Acid SCHEMBL29532685 | 0.97 | LMNA (0.65) | LMNAABCC4MAPTTSHRNFKB1 | |
| Adipic Acid SCHEMBL3293975 | 0.97 | LMNA (0.65) | LMNAABCC4MAPTTSHRNFKB1 | |
| Octanedioate SCHEMBL31348984 | 0.94 | TSHR (0.67) | LMNAABCC4MAPTTSHRNFKB1 | |
| Sebacic Acid SCHEMBL30655949 | 0.94 | TSHR (0.67) | LMNAABCC4MAPTTSHRNFKB1 | |
| Azelaic Acid SCHEMBL31688973 | 0.94 | TSHR (0.67) | LMNAABCC4MAPTTSHRNFKB1 | |
| Sebacic Acid SCHEMBL2776922 | 0.94 | TSHR (0.67) | LMNAABCC4MAPTTSHRNFKB1 | |
| Glutarate SCHEMBL28241209 | 0.92 | SLC22A6 (0.65) | LMNAABCC4MAPTTSHRNFKB1 | |
| Adipic Acid SCHEMBL8593870 | 0.85 | GPR84 (0.73) | LMNAABCC4MAPTTSHRNFKB1 | |
| Hexanoate SCHEMBL10395665 | 0.85 | AKR1B1 (0.73) | LMNAMAPTTSHRSLC22A6GPR84 | |
| Adipic Acid SCHEMBL7906482 | 0.85 | GPR84 (0.73) | LMNAABCC4MAPTTSHRNFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5055377-A | LIGHT-SENSITIVE RECORDING ELEMENT AND PROCESS OF FORMING A RELIEF IMAGE WHEREIN THE RECORDING ELEMENT CONTAINS LECITHIN AS AN ADDITIVE | BASF AKTIENGESELLSCHAFT (DE) | 1991-10-08 | — | — | US | disclosed |