Sebacic Acid

Sebacic Acid

SCHEMBL2776922

C=CC(=O)O.O=C(O)CCCCCCCCC(=O)O

nearest known ligand 0.67

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.67
LMNA P02545 4/20 0.67
NFKB1 P19838 1/20 0.67
PMP22 Q01453 1/20 0.67
ABCC4 O15439 1/20 0.65
MAPT P10636 1/20 0.65
GPR84 Q9NQS5 8/20 0.55
FFAR1 O14842 2/20 0.55
FFAR4 Q5NUL3 2/20 0.55
SLC22A6 Q4U2R8 2/20 0.53
PPARG P37231 6/20 0.52
PPARD Q03181 6/20 0.52
PPARA Q07869 6/20 0.52
HDAC11 Q96DB2 5/20 0.52
ALDH1A1 P00352 3/20 0.52
TLR2 O60603 2/20 0.52
TDP1 Q9NUW8 2/20 0.52
MEN1 O00255 2/20 0.52
FABP4 P15090 2/20 0.52
ALOX15 P16050 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Octanedioate SCHEMBL31348984 1.00 TSHR (0.67) TSHRLMNANFKB1PMP22ABCC4
Sebacic Acid SCHEMBL30655949 1.00 TSHR (0.67) TSHRLMNANFKB1PMP22ABCC4
Azelaic Acid SCHEMBL31688973 1.00 TSHR (0.67) TSHRLMNANFKB1PMP22ABCC4
Adipic Acid SCHEMBL3293975 0.97 LMNA (0.65) TSHRLMNANFKB1PMP22ABCC4
Adipic Acid SCHEMBL29532685 0.97 LMNA (0.65) TSHRLMNANFKB1PMP22ABCC4
Adipic Acid SCHEMBL9766376 0.94 LMNA (0.61) TSHRLMNANFKB1PMP22ABCC4
Glutarate SCHEMBL28241209 0.92 SLC22A6 (0.65) TSHRLMNANFKB1PMP22ABCC4
Adipic Acid SCHEMBL8593870 0.91 GPR84 (0.73) TSHRLMNANFKB1PMP22ABCC4
Adipic Acid SCHEMBL7906482 0.91 GPR84 (0.73) TSHRLMNANFKB1PMP22ABCC4
Acrylic Acid SCHEMBL31552907 0.91 GPR84 (0.73) TSHRLMNANFKB1PMP22ABCC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3784141-B1 APPLICATOR FOR DEPOSITING A LAYER OF ADHESIVE OR SEALANT COMPOSITION ON A BIOLOGICAL AND/OR PROSTHETIC TISSUE TISSIUM (FR) 2023-11-15 EP disclosed
CN-116023836-A Synthesis method of aqueous fluorine release agent and application of aqueous fluorine release agent in PET film 安徽省林田光电科技有限公司 2023-04-28 CN disclosed
WO-2021078962-A1 COMPOSITION COMPRISING ACTIVATED AND FUNCTIONALIZED PREPOLYMER TISSIUM SA (FR) 2021-04-29 WO disclosed
EP-3784141-A1 APPLICATOR FOR DEPOSITING A LAYER OF ADHESIVE OR SEALANT COMPOSITION ON A BIOLOGICAL AND/OR PROSTHETIC TISSUE Tissium SA (FR) 2021-03-03 EP disclosed
EP-3560427-A1 APPLICATOR FOR DEPOSITING A LAYER OF ADHESIVE OR SEALANT COMPOSITION ON A BIOLOGICAL AND/OR PROSTHETIC TISSUE Gecko Biomedical (FR) 2019-10-30 EP disclosed
CN-107743505-A Encapsulant composition 杰克高生物医学公司 2018-02-27 CN disclosed
US-9017726-B2 Biodegradable and thermosensitive poly(organophosphazene)-superparamagnetic nanoparticle complex, preparation method and use thereof KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2015-04-28 US disclosed
US-8586020-B2 Poly(organophosphazene) composition for biomaterials KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2013-11-19 US disclosed
CN-102892880-A Bioengineered tissue constructs and methods of making and using the same ORGANOGENESIS INC 2013-01-23 CN disclosed
US-20130004455-A1 POLY(ORGANOPHOSPHAZENE) COMPOSITION FOR BIOMATERIALS KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2013-01-03 US disclosed
EP-2540764-A2 Poly(organophosphazene) composition for biomaterials Korea Institute of Science and Technology (KR) 2013-01-02 EP disclosed
US-8313771-B2 Phosphazene hydrogels with chemical corss-link, preparation method thereof and use thereof KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2012-11-20 US disclosed
US-20120121517-A1 BIODEGRADABLE AND THERMOSENSITIVE POLY(ORGANOPHOSPHAZENE)-SUPERPARAMAGNETIC NANOPARTICLE COMPLEX, PREPARATION METHOD AND USE THEREOF Korean Institute of Science and Technology of Seoul, Republic of Korea 2012-05-17 US disclosed
US-20100297155-A1 PHOSPHAZENE HYDROGELS WITH CHEMICAL CORSS-LINK, PREPARATION METHOD THEREOF AND USE THEREOF DECA ITALIA S.R.L. (IT) 2010-11-25 US disclosed
WO-2010059738-A1 DIFFERENTIATION OF STEM CELLS INTO DOPAMINERGIC CELLS THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2010-05-27 WO disclosed
EP-2155806-A1 PHOSPHAZENE HYDROGELS WITH CHEMICAL CORSS -LINK, PREPARATION METHOD THEREOF AND USE THEREOF Korea Institute of Science and Technology (KR) 2010-02-24 EP disclosed
WO-2008153278-A1 PHOSPHAZENE HYDROGELS WITH CHEMICAL CORSS -LINK, PREPARATION METHOD THEREOF AND USE THEREOF KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2008-12-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130004455-A1 POLY(ORGANOPHOSPHAZENE) COMPOSITION FOR BIOMATERIALS PHOSPHO1, PGLS, PHYKPL TSHR 4580/4885LMNA 2870/4885NFKB1 4398/4885
US-20120121517-A1 BIODEGRADABLE AND THERMOSENSITIVE POLY(ORGANOPHOSPHAZENE)-SUPERPARAMAGNETIC NANOPARTICLE COMPLEX, PREPARATION METHOD AND USE THEREOF PHOSPHO1, HSPA2, FEM1B TSHR 929/4885LMNA 4134/4885NFKB1 3832/4885
US-20100297155-A1 PHOSPHAZENE HYDROGELS WITH CHEMICAL CORSS-LINK, PREPARATION METHOD THEREOF AND USE THEREOF PRUNE1, PHYKPL, PAPSS1 TSHR 3405/4885LMNA 4674/4885NFKB1 4684/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.