Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLYCD | O95822 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 4/20 | 0.33 |
| ▸ | ERBB2 | P04626 | 4/20 | 0.33 |
| ▸ | NAMPT | P43490 | 2/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.31 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.31 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9766565 | 0.87 | ALDH1A1 (0.49) | MLYCDALDH1A1HPGDHTTRAB9A | |
| SCHEMBL10384419 | 0.81 | CA1 (0.47) | ALDH1A1HTTRAB9ACYP2D6MEN1 | |
| SCHEMBL10384878 | 0.81 | POLB (0.42) | ALDH1A1HPGDHTTRAB9ACNR2 | |
| SCHEMBL10384260 | 0.81 | CES1 (0.41) | HPGDPRSS1KMT2A | |
| SCHEMBL9679848 | 0.79 | PPARA (0.42) | ALDH1A1HPGDRAB9A | |
| SCHEMBL9766563 | 0.79 | TAS1R3 (0.42) | MLYCDALDH1A1HTTKDM4EMEN1 | |
| SCHEMBL9681301 | 0.78 | MLYCD (0.45) | MLYCDALDH1A1HPGDHTTRAB9A | |
| SCHEMBL9766582 | 0.77 | MLYCD (0.32) | MLYCDALDH1A1 | |
| SCHEMBL9766551 | 0.76 | ALDH1A1 (0.43) | ALDH1A1HPGDHTTRAB9AMEN1 | |
| SCHEMBL17502989 | 0.74 | HPGD (0.48) | MLYCDALDH1A1HPGDHTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5145885-A | Morpholine compound, binders | CIBA-GEIGY CORPORATION (US) | 1992-09-08 | — | — | US | disclosed |
| US-4992547-A | Aminoaryl ketone photoinitiators | CIBA-GEIGY CORPORATION (US) | 1991-02-12 | — | — | US | disclosed |