Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.32 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.32 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.32 |
| ▸ | ACACB | O00763 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9158975 | 0.90 | PTGS2 (0.37) | P2RX7 | |
| SCHEMBL12891847 | 0.89 | SLC6A2 (0.36) | P2RX7 | |
| SCHEMBL12891848 | 0.89 | SLC6A2 (0.36) | P2RX7 | |
| SCHEMBL9158474 | 0.80 | PTGS2 (0.36) | P2RX7ACACB | |
| SCHEMBL10479801 | 0.79 | HTR2A (0.34) | — | |
| SCHEMBL9155759 | 0.78 | PTGS2 (0.35) | ACACB | |
| SCHEMBL9253040 | 0.77 | TRPV3 (0.33) | TRPV3 | |
| SCHEMBL9157491 | 0.77 | PTGS2 (0.35) | ACACB | |
| SCHEMBL8774169 | 0.76 | GRIN2B (0.36) | TRPV3ACACB | |
| SCHEMBL9158940 | 0.76 | GAA (0.35) | ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0445248-A1 | PYRIDINE DERIVATIVES. | MERCK PATENT GMBH (DE) | 1991-09-11 | — | — | EP | disclosed |