Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.41 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9158938 | 0.93 | RAB9A (0.50) | RAB9AMAPTL3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL9154059 | 0.93 | LMNA (0.50) | RAB9AMAPTL3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL9155401 | 0.90 | RAB9A (0.49) | RAB9AMAPTL3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL9154338 | 0.90 | RAB9A (0.50) | RAB9AMAPTL3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL9766695 | 0.83 | MAPT (0.52) | RAB9AMAPTL3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL9875386 | 0.80 | RAB9A (0.53) | RAB9AMAPTL3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL9158922 | 0.80 | NFKB1 (0.51) | RAB9AMAPTL3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL10715445 | 0.80 | RAB9A (0.52) | RAB9AMAPTL3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL10714361 | 0.80 | MAPT (0.48) | RAB9AMAPTL3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL10715074 | 0.80 | MAPT (0.48) | RAB9AMAPTL3MBTL1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0445248-A1 | PYRIDINE DERIVATIVES. | MERCK PATENT GMBH (DE) | 1991-09-11 | — | — | EP | disclosed |