Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.42 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 3/20 | 0.35 |
| ▸ | MMP2 | P08253 | 2/20 | 0.35 |
| ▸ | MMP12 | P39900 | 2/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.34 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.34 |
| ▸ | LTB4R | Q15722 | 3/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9671527 | 0.79 | CA2 (0.40) | GPR84S1PR2S1PR1FFAR1CYSLTR2 | |
| SCHEMBL9671129 | 0.79 | CA2 (0.40) | GPR84S1PR2S1PR1FFAR1CYSLTR2 | |
| SCHEMBL7301168 | 0.79 | CA2 (0.40) | GPR84S1PR2S1PR1FFAR1CYSLTR2 | |
| SCHEMBL9838027 | 0.78 | HDAC1 (0.32) | — | |
| Benzene SCHEMBL9326381 | 0.76 | ALDH1A1 (0.36) | GPR84LTB4R | |
| SCHEMBL9670950 | 0.75 | GLS2 (0.35) | LTB4R | |
| SCHEMBL7295059 | 0.75 | GLS2 (0.35) | LTB4R | |
| SCHEMBL9326264 | 0.75 | MMP2 (0.36) | MMP9MMP2 | |
| SCHEMBL9325034 | 0.75 | GLS2 (0.35) | LTB4R | |
| SCHEMBL9671037 | 0.75 | GLS2 (0.35) | LTB4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5013850-A | 4-ethyl and 4-ethenyl-5-hydroxy-2(5H)-furanones substituted on alpha carbon of the ethyl or ethenyl side chain with a long chain alkyl group and on the beta carbon with a polar group, as anti-inflammatory agents | ALLERGAN, INC. (US) | 1991-05-07 | — | — | US | disclosed |