Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.55 |
| ▸ | ACHE | P22303 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | RGS12 | O14924 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | THPO | P40225 | 1/20 | 0.40 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Toluene SCHEMBL11434586 | 0.85 | LMNA (0.55) | LMNATSHRALOX12ACHEHPGD | |
| Toluene SCHEMBL50431 | 0.84 | LMNA (0.69) | LMNATSHRALOX12ACHEHPGD | |
| Toluene SCHEMBL11298633 | 0.81 | LMNA (0.65) | LMNATSHRALOX12ACHEHPGD | |
| Toluene SCHEMBL6795640 | 0.81 | LMNA (0.65) | LMNATSHRALOX12ACHEHPGD | |
| Toluene SCHEMBL11305018 | 0.81 | LMNA (0.65) | LMNATSHRALOX12ACHEHPGD | |
| Toluene SCHEMBL246259 | 0.81 | LMNA (0.65) | LMNATSHRALOX12ACHEHPGD | |
| Toluene SCHEMBL11179986 | 0.80 | TSHR (0.55) | LMNATSHRALOX12ACHEHPGD | |
| Phenol SCHEMBL5874437 | 0.80 | GLA (0.55) | LMNATSHRALOX12ADRA2CCHRM2 | |
| Toluene SCHEMBL11305945 | 0.79 | LMNA (0.61) | LMNATSHRALOX12ACHEHPGD | |
| Toluene SCHEMBL672208 | 0.79 | TSHR (0.61) | LMNATSHRALOX12ACHEHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5068062-A | Crosslinked resin containing 4,4*-diaminodiphenylmethane units with the amine quaternized and an electrolytic material | TEIJIN LIMITED (JP) | 1991-11-26 | — | — | US | disclosed |