Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 15/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9767412 | 0.81 | DRD2 (0.38) | ABCB1KDM4EDRD2DRD3 | |
| SCHEMBL13594010 | 0.80 | ABCB1 (0.42) | ABCB1KDM4EDRD2DRD3 | |
| SCHEMBL9767096 | 0.76 | DRD2 (0.38) | ABCB1DRD2DRD3 | |
| SCHEMBL9767519 | 0.73 | ABCB1 (0.39) | ABCB1KDM4E | |
| SCHEMBL9767517 | 0.73 | ABCB1 (0.39) | ABCB1KDM4E | |
| SCHEMBL10912448 | 0.72 | ABCB1 (0.36) | ABCB1 | |
| SCHEMBL482249 | 0.68 | ABCB1 (0.56) | ABCB1KDM4E | |
| SCHEMBL4023253 | 0.68 | ABCB1 (0.56) | ABCB1KDM4E | |
| SCHEMBL9371324 | 0.68 | ABCB1 (0.56) | ABCB1KDM4E | |
| SCHEMBL481900 | 0.68 | ABCB1 (0.56) | ABCB1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5072006-A | Chemical intermeidate; hypotensive agents, muscle relaxants | RECHERCHE SYNTEX FRANCE S.A. (FR) | 1991-12-10 | — | — | US | disclosed |
| US-4997846-A | Smooth muscle relaxants, hypotensives | RESEARCHE SYNTEX FRANCE, S.A. (FR) | 1991-03-05 | — | — | US | disclosed |
| EP-0377966-A2 | Novel benzopyranylpyrrolinone derivatives | RECHERCHE SYNTEX FRANCE SA (FR) | 1990-07-18 | — | — | EP | disclosed |