Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 6/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MGAM | O43451 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SI | P14410 | 1/20 | 0.34 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | POLA1 | P09884 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18076264 | 1.00 | ALDH1A1 (0.46) | ALDH1A1LMNATSHRHSD17B10MGAM | |
| SCHEMBL8136448 | 0.81 | TSHR (0.39) | ALDH1A1LMNATSHRHSD17B10MGAM | |
| SCHEMBL2592556 | 0.81 | TSHR (0.39) | ALDH1A1LMNATSHRHSD17B10MGAM | |
| SCHEMBL24438525 | 0.80 | ALDH1A1 (0.47) | ALDH1A1LMNATSHRHSD17B10MGAM | |
| SCHEMBL12925787 | 0.80 | GAA (0.41) | ALDH1A1LMNATSHRHSD17B10MGAM | |
| SCHEMBL14209811 | 0.80 | LMNA (0.40) | ALDH1A1LMNATSHRCYP3A4CYP2C19 | |
| SCHEMBL28243 | 0.79 | TSHR (0.50) | ALDH1A1LMNATSHRHSD17B10MGAM | |
| SCHEMBL11361190 | 0.79 | CA1 (0.35) | TSHRCYP3A4CYP2C19 | |
| SCHEMBL3186126 | 0.79 | ALDH1A1 (0.46) | ALDH1A1LMNATSHRHSD17B10MGAM | |
| SCHEMBL374306 | 0.79 | ALDH1A1 (0.46) | ALDH1A1LMNATSHRHSD17B10MGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109810090-A | One kind (3R, 9R) -3- hydroxyl -7- oxo -9- methyl decalactone and preparation method thereof | 绍兴文理学院 | 2019-05-28 | — | — | CN | claimed |
| US-11913055-B2 | Continuous flow method for preparing (R)-3-hydroxy-5-hexenoate | FUDAN UNIVERSITY (CN) | 2024-02-27 | — | — | US | disclosed |
| US-20220033863-A1 | CONTINUOUS FLOW METHOD FOR PREPARING (R)-3-HYDROXY-5-HEXENOATE | FUDAN UNIVERSITY (CN) | 2022-02-03 | — | — | US | disclosed |
| CN-108359626-B | Engineering bacterium and application thereof in preparation of (R) -3-hydroxy-5-hexenoic acid ester | 复旦大学 | 2021-10-26 | — | — | CN | disclosed |
| CN-111686809-A | Carbonyl reductase/isopropanol dehydrogenase co-immobilized catalyst and preparation method and application thereof | 复旦大学 | 2020-09-22 | — | — | CN | disclosed |
| CN-109810090-A | One kind (3R, 9R) -3- hydroxyl -7- oxo -9- methyl decalactone and preparation method thereof | 绍兴文理学院 | 2019-05-28 | — | — | CN | disclosed |
| CN-108359626-A | It a kind of engineering bacteria and its is preparing（R）Application in -3- hydroxyl -5- hexene acid esters | 复旦大学 | 2018-08-03 | — | — | CN | disclosed |
| US-9932361-B2 | Convenient process for the preparation of statins | F.I.S. - FABBRICA ITALIANA SINTETICI S.P.A. (IT) | 2018-04-03 | — | — | US | disclosed |
| EP-2867231-B1 | CONVENIENT PROCESS FOR THE PREPARATION OF STATINS | F I S - FABBRICA ITALIANA SINTETICI S P A (IT) | 2017-01-04 | — | — | EP | disclosed |
| US-20160200744-A1 | CONVENIENT PROCESS FOR THE PREPARATION OF STATINS | F.I.S. - FABBRICA ITALIANA SINTETICI S.P.A. (IT) | 2016-07-14 | — | — | US | disclosed |
| US-20150344439-A1 | Convenient Process for the Preparation of Statins | F.I.S. - FABBRICA ITALIANA SINTETICI S.P.A. (IT) | 2015-12-03 | — | — | US | disclosed |
| US-20150344439-A1 | Convenient Process for the Preparation of Statins | F.I.S. - FABBRICA ITALIANA SINTETICI S.P.A. (IT) | 2015-12-03 | — | — | US | disclosed |
| US-8933269-B2 | Rosuvastatin calcium intermediate and method for preparing the same | PORTON FINE CHEMICALS LTD. (CN) | 2015-01-13 | — | — | US | disclosed |
| US-8933269-B2 | Rosuvastatin calcium intermediate and method for preparing the same | PORTON FINE CHEMICALS LTD. (CN) | 2015-01-13 | — | — | US | disclosed |
| WO-2014128022-A1 | CONVENIENT PROCESS FOR THE PREPARATION OF STATINS | F.I.S. - FABBRICA ITALIANA SINTETICI S.P.A. (IT) | 2014-08-28 | — | — | WO | disclosed |
| EP-2557084-B1 | ROSUVASTATIN CALCIUM INTERMEDIATE AND PREPARATION METHOD THEREOF | PORTON FINE CHEMICALS LTD (CN) | 2014-06-18 | — | — | EP | disclosed |
| EP-2557084-A1 | ROSUVASTATIN CALCIUM INTERMEDIATE AND PREPARATION METHOD THEREOF | Porton Fine Chemicals Ltd (CN) | 2013-02-13 | — | — | EP | disclosed |
| US-20120310000-A1 | ROSUVASTATIN CALCIUM INTERMEDIATE AND METHOD FOR PREPARING THE SAME | PORTON FINE CHEMICALS LTD. (CN) | 2012-12-06 | — | — | US | disclosed |
| US-20120310000-A1 | ROSUVASTATIN CALCIUM INTERMEDIATE AND METHOD FOR PREPARING THE SAME | PORTON FINE CHEMICALS LTD. (CN) | 2012-12-06 | — | — | US | disclosed |
| US-20110009593-A1 | Polymeric Bioplastics | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2011-01-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150344439-A1 | Convenient Process for the Preparation of Statins | HMGCR, PCSK9, FDPS | ALDH1A1 1160/4885LMNA 709/4885TSHR 3356/4885 |
| US-20120310000-A1 | ROSUVASTATIN CALCIUM INTERMEDIATE AND METHOD FOR PREPARING THE SAME | ROS1, KCNN2, KCNN4 | ALDH1A1 2438/4885LMNA 407/4885TSHR 3934/4885 |
| US-20160200744-A1 | CONVENIENT PROCESS FOR THE PREPARATION OF STATINS | HMGCR, PCSK9, FDPS | ALDH1A1 1160/4885LMNA 709/4885TSHR 3356/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.