Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 7/20 | 0.67 |
| ▸ | OPRK1 | P41145 | 7/20 | 0.67 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.48 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9767727 | 0.85 | SIGMAR1 (0.66) | OPRM1OPRK1SIGMAR1OPRD1 | |
| Hydrochloric Acid SCHEMBL9767758 | 0.85 | SIGMAR1 (0.65) | OPRM1OPRK1SIGMAR1OPRD1 | |
| SCHEMBL9767788 | 0.82 | OPRM1 (0.66) | OPRM1OPRK1SIGMAR1 | |
| SCHEMBL9772298 | 0.79 | SIGMAR1 (0.50) | OPRM1OPRK1SIGMAR1OPRD1 | |
| SCHEMBL9772412 | 0.78 | KMT2A (0.58) | OPRM1OPRK1SIGMAR1OPRD1 | |
| Hydrochloric Acid SCHEMBL9772305 | 0.77 | KMT2A (0.57) | OPRM1OPRK1SIGMAR1OPRD1 | |
| SCHEMBL9772344 | 0.76 | SIGMAR1 (0.61) | OPRM1OPRK1SIGMAR1OPRD1 | |
| SCHEMBL9494728 | 0.76 | SIGMAR1 (0.67) | OPRM1OPRK1SIGMAR1OPRD1 | |
| SCHEMBL9702348 | 0.76 | SIGMAR1 (0.67) | OPRM1OPRK1SIGMAR1OPRD1 | |
| SCHEMBL9767784 | 0.74 | SIGMAR1 (0.66) | OPRM1OPRK1SIGMAR1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4988727-A | Cardiovascular disorders, analgesics | ROUSSEL UCLAF (FR) | 1991-01-29 | — | — | US | disclosed |
| US-4888355-A | Indanes and their use as antiarrhythmic agents | ROUSSEL UCLAF (FR) | 1989-12-19 | — | — | US | disclosed |