Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM2 | O94759 | 4/20 | 0.55 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.55 |
| ▸ | TRPA1 | O75762 | 9/20 | 0.54 |
| ▸ | TRPM8 | Q7Z2W7 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | APEX1 | P27695 | 2/20 | 0.53 |
| ▸ | RECQL | P46063 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9767884 | 0.81 | TRPM2 (0.60) | TRPM2LTB4RTRPA1TRPM8MEN1 | |
| SCHEMBL13320651 | 0.81 | TRPM2 (0.60) | TRPM2LTB4RTRPA1TRPM8MEN1 | |
| SCHEMBL294402 | 0.76 | TRPM2 (0.83) | TRPM2LTB4RTRPA1TRPM8MEN1 | |
| SCHEMBL294403 | 0.76 | TRPM2 (0.83) | TRPM2LTB4RTRPA1TRPM8MEN1 | |
| SCHEMBL8635715 | 0.75 | TRPA1 (0.78) | TRPM2LTB4RTRPA1TRPM8MEN1 | |
| SCHEMBL8635718 | 0.75 | TRPA1 (0.78) | TRPM2LTB4RTRPA1TRPM8MEN1 | |
| SCHEMBL13320698 | 0.74 | TRPM2 (0.55) | TRPM2LTB4RTRPA1TRPM8MEN1 | |
| SCHEMBL31210242 | 0.74 | MMP1 (0.58) | MEN1KMT2ASMN1; SMN2KDM4ERECQL | |
| Salicylic Acid SCHEMBL2250046 | 0.73 | KDM4E (0.45) | MEN1KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL13320712 | 0.73 | TRPM2 (0.72) | TRPM2LTB4RTRPA1TRPM8MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5006548-A | Hyaluronidase inhibitors, antiallergens, immunomodulators | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1991-04-09 | — | — | US | disclosed |
| EP-0153850-B1 | ACRYLAMIDOBENZOIC ACID DERIVATIVES AND THEIR USE | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1989-09-13 | — | — | EP | disclosed |
| EP-0153850-A1 | Acrylamidobenzoic acid derivatives and their use | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1985-09-04 | — | — | EP | disclosed |