Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM2 | O94759 | 4/20 | 0.60 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.60 |
| ▸ | TRPA1 | O75762 | 9/20 | 0.59 |
| ▸ | TRPM8 | Q7Z2W7 | 5/20 | 0.59 |
| ▸ | NPC1 | O15118 | 4/20 | 0.58 |
| ▸ | RAB9A | P51151 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 4/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | APEX1 | P27695 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13320651 | 1.00 | TRPM2 (0.60) | TRPM2LTB4RTRPA1TRPM8NPC1 | |
| SCHEMBL6582936 | 0.82 | NPC1 (0.51) | NPC1RAB9AKDM4EMAPTRECQL | |
| SCHEMBL6582938 | 0.82 | NPC1 (0.51) | NPC1RAB9AKDM4EMAPTRECQL | |
| SCHEMBL9767825 | 0.81 | TRPM2 (0.55) | TRPM2LTB4RTRPA1TRPM8NPC1 | |
| SCHEMBL13320698 | 0.81 | TRPM2 (0.55) | TRPM2LTB4RTRPA1TRPM8NPC1 | |
| SCHEMBL13352230 | 0.81 | MMP1 (0.64) | NPC1RAB9AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL294402 | 0.80 | TRPM2 (0.83) | TRPM2LTB4RTRPA1TRPM8NPC1 | |
| SCHEMBL294403 | 0.80 | TRPM2 (0.83) | TRPM2LTB4RTRPA1TRPM8NPC1 | |
| SCHEMBL13320712 | 0.80 | TRPM2 (0.72) | TRPM2LTB4RTRPA1TRPM8NPC1 | |
| SCHEMBL8635718 | 0.79 | TRPA1 (0.78) | TRPM2LTB4RTRPA1TRPM8NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5006548-A | Hyaluronidase inhibitors, antiallergens, immunomodulators | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1991-04-09 | — | — | US | disclosed |
| EP-0153850-B1 | ACRYLAMIDOBENZOIC ACID DERIVATIVES AND THEIR USE | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1989-09-13 | — | — | EP | disclosed |