Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAM17 | P78536 | 2/20 | 0.47 |
| ▸ | MMP8 | P22894 | 2/20 | 0.47 |
| ▸ | MMP13 | P45452 | 2/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GRK2 | P25098 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | PTGES | O14684 | 1/20 | 0.38 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9768486 | 0.80 | PTGIR (0.55) | ALDH1A1MMP1GAAPPARGPPARA | |
| SCHEMBL187687 | 0.77 | ALDH3A1 (0.50) | ALDH1A1KMT2AMAOBP2RX3MEN1 | |
| SCHEMBL9813770 | 0.76 | PTGIR (0.54) | ALDH1A1MMP1GAAPTGES | |
| SCHEMBL9768504 | 0.76 | ALDH1A1 (0.40) | ALDH1A1MMP1KMT2APOLBGRK2 | |
| SCHEMBL11403419 | 0.76 | LTA4H (0.47) | ALDH1A1KMT2AMAOBP2RX3MEN1 | |
| SCHEMBL362669 | 0.76 | ALDH1A1 (0.54) | ALDH1A1MMP1KMT2APOLBGRK2 | |
| SCHEMBL9813451 | 0.75 | CA2 (0.51) | ALDH1A1KMT2APOLBGRK2GAA | |
| SCHEMBL9768512 | 0.75 | MGLL (0.50) | ALDH1A1KMT2APOLBGRK2GAA | |
| SCHEMBL10584133 | 0.75 | KMT2A (0.58) | ALDH1A1KMT2APOLBGRK2GAA | |
| SCHEMBL9320853 | 0.75 | GAA (0.62) | ALDH1A1KMT2AGAAMEN1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5070099-A | THROMBOXANE ANTAGONISTS | E. R. SQUIBB & SONS, INC. (US) | 1991-12-03 | — | — | US | disclosed |