Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 5/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 12/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1544768 | 0.83 | PTGS2 (0.47) | HSD11B1PTGS2ALDH1A1PTGS1 | |
| SCHEMBL4172936 | 0.83 | HSD11B1 (0.43) | HSD11B1PTGS2ALDH1A1 | |
| SCHEMBL919281 | 0.83 | HSD11B1 (0.49) | HSD11B1PTGS2ALDH1A1PTGS1 | |
| SCHEMBL11527657 | 0.81 | HSD11B1 (0.43) | HSD11B1PTGS2ALDH1A1 | |
| SCHEMBL1544452 | 0.81 | ALDH1A1 (0.43) | HSD11B1ALDH1A1 | |
| SCHEMBL9446340 | 0.80 | LMNA (0.46) | HSD11B1PTGS2ALDH1A1 | |
| SCHEMBL9224169 | 0.75 | HSD11B1 (0.51) | HSD11B1PTGS2ALDH1A1 | |
| SCHEMBL1999427 | 0.75 | HSD11B1 (0.35) | HSD11B1PTGS2ALDH1A1 | |
| SCHEMBL18912121 | 0.74 | HSD11B1 (0.59) | HSD11B1ALDH1A1 | |
| SCHEMBL1544502 | 0.73 | PTGS2 (0.38) | HSD11B1PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4981863-A | ANTIANXIETY | MERRELL DOW PHARMACEUTICALS (US) | 1991-01-01 | — | — | US | disclosed |