Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.35 |
| ▸ | CDC25A | P30304 | 1/20 | 0.35 |
| ▸ | CDC25B | P30305 | 1/20 | 0.35 |
| ▸ | ALPG | P10696 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9768640 | 0.81 | HSD11B1 (0.50) | HSD11B1ALDH1A1PTGS2 | |
| SCHEMBL1544768 | 0.78 | PTGS2 (0.47) | HSD11B1ALDH1A1PTGS2 | |
| SCHEMBL4172936 | 0.78 | HSD11B1 (0.43) | HSD11B1ALDH1A1PTGS2HPGDKDM4E | |
| SCHEMBL11521194 | 0.78 | HSD11B1 (0.53) | HSD11B1ALDH1A1CDC25ACDC25BALPG | |
| SCHEMBL919281 | 0.78 | HSD11B1 (0.49) | HSD11B1ALDH1A1PTGS2 | |
| SCHEMBL1544452 | 0.76 | ALDH1A1 (0.43) | HSD11B1ALDH1A1CDC25ACDC25BSMN1; SMN2 | |
| SCHEMBL11523865 | 0.73 | PGR (0.41) | HSD11B1ALDH1A1CDC25ACDC25BALPG | |
| SCHEMBL1999427 | 0.70 | HSD11B1 (0.35) | HSD11B1ALDH1A1PTGS2SMN1; SMN2TP53 | |
| SCHEMBL11525861 | 0.69 | HDAC1 (0.39) | ALDH1A1ADORA2AADORA2BSMN1; SMN2TP53 | |
| SCHEMBL7466436 | 0.69 | ABCC9 (0.50) | HSD11B1ALDH1A1TDP1PTGS2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4159985-A | Heterocyclic phenyl ester ultraviolet stabilizers | EASTMAN KODAK COMPANY (US) | 1979-07-03 | — | — | US | disclosed |
| US-4140674-A | FOR POLYMERS | EASTMAN KODAK COMPANY (US) | 1979-02-20 | — | — | US | disclosed |
| US-4020080-A | Oxadiazolylphenyl aromatic ester compounds and their use as ultraviolet stabilizer in organic compositions | EASTMAN KODAK COMPANY (US) | 1977-04-26 | — | — | US | disclosed |