Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 3/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.31 |
| ▸ | HTR2B | P41595 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16263333 | 0.83 | PKM (0.35) | TSHRPKMMEN1KMT2AMAOB | |
| SCHEMBL25718526 | 0.80 | TSHR (0.38) | HTR7TSHRPKMKDM4EMAPT | |
| SCHEMBL11180883 | 0.78 | ADRA2A (0.43) | KCNH2ADRA2ASLC6A2HTR2ASLC6A4 | |
| SCHEMBL10849656 | 0.77 | MEN1 (0.47) | CYP3A4KCNH2HTR2BMEN1KMT2A | |
| SCHEMBL8309740 | 0.77 | PKM (0.36) | TSHRPKMKMT2AMAOBABCG2 | |
| SCHEMBL9724429 | 0.77 | PKM (0.38) | TSHRPKMKDM4EKMT2AALDH1A1 | |
| SCHEMBL295321 | 0.77 | PKM (0.38) | TSHRPKMKMT2ALMNAMAOB | |
| SCHEMBL9768971 | 0.77 | PKM (0.38) | TSHRPKMKMT2AADRA2ASIGMAR1 | |
| SCHEMBL10849661 | 0.75 | GAA (0.47) | KDM4ECYP3A4MAPTALDH1A1CHRM2 | |
| Hydrochloric Acid SCHEMBL15054537 | 0.75 | PKM (0.37) | TSHRPKMKDM4EKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5030625-A | Applying to phytopathogen | SANDOZ LTD. (CH) | 1991-07-09 | — | — | US | disclosed |
| US-4684661-A | Anti-fungal homopropargylamines, compositions, and method of use therefor | SANDOZ LTD. (CH) | 1987-08-04 | — | — | US | disclosed |
| EP-0191269-A2 | Novel homopropargylamines | SANDOZ AG (CH) | 1986-08-20 | — | — | EP | disclosed |