Methacrylic Acid

Methacrylic Acid

SCHEMBL9769602

C=C(C)C(=O)O.C=COC(=O)c1ccc(CCC)cc1C/C=C/C(=O)O

nearest known ligand 0.34

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 2/20 0.34
MCL1 Q07820 1/20 0.32
SMN1; SMN2 Q16637 2/20 0.31
NPC1 O15118 1/20 0.31
MAPT P10636 1/20 0.31
CASP3 P42574 1/20 0.31
RAB9A P51151 1/20 0.31
SENP8 Q96LD8 1/20 0.31
SENP7 Q9BQF6 1/20 0.31
SENP6 Q9GZR1 1/20 0.31
KDM4E B2RXH2 1/20 0.31
MITF O75030 1/20 0.31
ALDH1A1 P00352 1/20 0.31
HPGD P15428 1/20 0.31
KLF5 Q13887 1/20 0.31
PPARA Q07869 2/20 0.31
PPARG P37231 1/20 0.31
CNR1 P21554 1/20 0.30
CNR2 P34972 1/20 0.30
KAT8 Q9H7Z6 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9769597 0.86 PTGS2 (0.33) MAPTALDH1A1HPGD
SCHEMBL9769604 0.78 PTGER1 (0.41) THRBSMN1; SMN2MAPTKDM4EALDH1A1
SCHEMBL9769680 0.75 NR1H4 (0.39) SMN1; SMN2
SCHEMBL7617402 0.74 RXRA (0.37) PPARG
Acrylic Acid SCHEMBL9769683 0.70 PTGER4 (0.40) SMN1; SMN2MAPTKDM4EALDH1A1
Vinyl Ether SCHEMBL3175883 0.69 PTGER4 (0.39) SMN1; SMN2MAPTKDM4EALDH1A1
SCHEMBL441100 0.67 PPARA (0.38) THRBMCL1SMN1; SMN2MAPTKDM4E
SCHEMBL9255620 0.67 MEN1 (0.35) THRBALDH1A1PLA2G1BATG4B
SCHEMBL22889058 0.66 AKR1B10 (0.48) THRBMAPTKDM4EALDH1A1HPGD
SCHEMBL9769653 0.65 CYP3A4 (0.46) SMN1; SMN2MAPTKDM4EALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5006433-A Printing plate precursors for electrophotographic plate-making purposes FUJI PHOTO FILM CO., LTD. (JP) 1991-04-09 US disclosed