SCHEMBL9769604

SCHEMBL9769604

C=COC(=O)c1ccc(C)cc1C/C=C/C(=O)O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGER1 P34995 3/20 0.41
PTGER4 P35408 3/20 0.41
PTGER3 P43115 3/20 0.41
PTGER2 P43116 3/20 0.41
MAPT P10636 2/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
GAA P10253 1/20 0.35
HPGD P15428 2/20 0.34
SRC P12931 2/20 0.33
L3MBTL1 Q9Y468 2/20 0.33
MAPK1 P28482 1/20 0.33
CSNK2A1 P68400 1/20 0.33
NFE2L2 Q16236 1/20 0.33
ALDH1A1 P00352 4/20 0.33
LMNA P02545 3/20 0.33
THRB P10828 1/20 0.33
HTT P42858 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
KDM4E B2RXH2 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9769597 0.86 PTGS2 (0.33) PTGER1PTGER4PTGER3PTGER2MAPT
SCHEMBL9769653 0.85 CYP3A4 (0.46) PTGER1PTGER4PTGER3PTGER2MAPT
SCHEMBL9769680 0.84 NR1H4 (0.39) SMN1; SMN2MAPK1NPSR1TDP1
SCHEMBL7617402 0.80 RXRA (0.37) MAPK1NPSR1TDP1
Acrylic Acid SCHEMBL9769683 0.78 PTGER4 (0.40) PTGER1PTGER4PTGER3PTGER2MAPT
Methacrylic Acid SCHEMBL9769602 0.78 THRB (0.34) MAPTSMN1; SMN2HPGDALDH1A1THRB
Vinyl Ether SCHEMBL3175883 0.77 PTGER4 (0.39) PTGER1PTGER4PTGER3PTGER2MAPT
SCHEMBL1285885 0.75 TAAR1 (0.46) PTGER1PTGER4PTGER3PTGER2MAPT
SCHEMBL7770963 0.74 NFE2L2 (0.44) MAPTSMN1; SMN2HPGDNFE2L2HTT
SCHEMBL3354334 0.73 PTGER4 (0.53) PTGER1PTGER4PTGER3PTGER2SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5006433-A Printing plate precursors for electrophotographic plate-making purposes FUJI PHOTO FILM CO., LTD. (JP) 1991-04-09 US disclosed