Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 4/20 | 0.42 |
| ▸ | CTSS | P25774 | 3/20 | 0.42 |
| ▸ | TACR3 | P29371 | 1/20 | 0.41 |
| ▸ | REN | P00797 | 1/20 | 0.40 |
| ▸ | PTPRB | P23467 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | SYK | P43405 | 1/20 | 0.38 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | CCR2 | P41597 | 1/20 | 0.35 |
| ▸ | NPFFR1 | Q9GZQ6 | 1/20 | 0.35 |
| ▸ | NPFFR2 | Q9Y5X5 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9779450 | 0.89 | CTSK (0.45) | CYP3A4CYP2D6CYP2C9ALOX15TSHR | |
| SCHEMBL28237555 | 0.81 | CTSS (0.54) | CTSKCTSSCTSLSYKKLK5 | |
| SCHEMBL7158579 | 0.79 | CTSK (0.45) | CYP3A4CYP2D6CYP2C9ALOX15TSHR | |
| SCHEMBL4152673 | 0.78 | TACR3 (0.40) | CYP3A4CYP2D6CYP2C9ALOX15TSHR | |
| SCHEMBL9769981 | 0.76 | TACR3 (0.43) | CYP3A4CYP2D6CYP2C9ALOX15TSHR | |
| SCHEMBL9779446 | 0.75 | CTSS (0.51) | CYP3A4CYP2D6CYP2C9ALOX15TSHR | |
| SCHEMBL3220161 | 0.75 | CTSK (0.48) | CYP3A4CYP2D6CYP2C9ALOX15TSHR | |
| SCHEMBL3685468 | 0.75 | CTSK (0.48) | CYP3A4CYP2D6CYP2C9ALOX15TSHR | |
| SCHEMBL11522699 | 0.75 | CTSK (0.46) | CYP3A4CYP2D6CYP2C9ALOX15TSHR | |
| SCHEMBL1789747 | 0.75 | CTSK (0.48) | CYP3A4CYP2D6CYP2C9ALOX15TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4987134-A | DISORDERS OF BRAIN FUNCTIONS | CASSELLA AKTIENGESELLSCHAFT (DE) | 1991-01-22 | — | — | US | disclosed |