Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.46 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | PPARD | Q03181 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9480490 | 0.89 | BACE1 (0.80) | BACE1KMT2AHSD17B10NPC1RAB9A | |
| SCHEMBL14546451 | 0.86 | LMNA (0.53) | BACE1KMT2AHSD17B10LMNACYP2D6 | |
| SCHEMBL9770465 | 0.84 | BACE1 (0.76) | BACE1KMT2AHSD17B10NPC1RAB9A | |
| SCHEMBL13853192 | 0.82 | MAPT (0.49) | BACE1KMT2AHSD17B10LMNACYP2D6 | |
| SCHEMBL5476778 | 0.81 | NPC1 (0.68) | BACE1KMT2AHSD17B10NPC1RAB9A | |
| SCHEMBL10338981 | 0.81 | BACE1 (0.61) | BACE1KMT2AHSD17B10NPC1RAB9A | |
| SCHEMBL9770321 | 0.81 | BACE1 (0.76) | BACE1KMT2AHSD17B10NPC1RAB9A | |
| SCHEMBL24098294 | 0.81 | MAOA (0.48) | BACE1MAPT | |
| SCHEMBL9770570 | 0.80 | BACE1 (0.76) | BACE1KMT2AHSD17B10NPC1RAB9A | |
| SCHEMBL15263225 | 0.80 | ADRB2 (0.52) | BACE1KMT2ARAB9ALMNACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2139878-A2 | HIGH REFRACTIVE INDEX MONOMERS, COMPOSITIONS AND USES THEREOF | BASF SE (DE) | 2010-01-06 | — | — | EP | disclosed |
| WO-2008101806-A2 | HIGH REFRACTIVE INDEX MONOMERS, COMPOSITIONS AND USES THEREOF | BASF SE (CH) | 2008-08-28 | — | — | WO | disclosed |
| US-20080200582-A1 | High refractive index monomers, compositions and uses thereof | CIBA CORP. | 2008-08-21 | — | — | US | disclosed |